Evidence map›Paper›PMID 34806632›Full record

ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2022

Computational analysis of aortic haemodynamics in the presence of ascending aortic aneurysm.

Aleksandra Petuchova, Algirdas Maknickas

Open access · bronzeAbstract read
In one paragraph

Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aleksandra PetuchovaDepartment of Biomechanical Engineering, Faculty of Mechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania.
Algirdas MaknickasDepartment of Biomechanical Engineering, Faculty of Mechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania.
Vilnius Gediminas Technical University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe usefulness of numerical modelling of a patient's cardiovascular system is growing in clinical treatment. Understanding blood flow mechanics can be crucial in identifying connections between haemodynamic factors and aortic wall pathologies.

objectiveThis work investigates the haemodynamic parameters of an ascending aorta and ascending aortic aneurysm in humans.

methodsTwo aortic models were constructed from medical images using the SimVascular software. FEM blood flow modelling of cardiac cycle was performed using CFD and CMM-FSI at different vascular wall parameters.

resultsThe results showed that highest blood velocity was 1.18 m/s in aorta with the aneurysm and 1.9 m/s in healthy aorta model. The largest displacements ware in the aorta with the aneurysm (0.73 mm). In the aorta with the aneurysm, time averaged WSS values throughout the artery range from 0 Pa to 1 Pa. In the healthy aorta, distribution of WSS values changes from 0.3 Pa to 0.6 Pa.

conclusionsIn the case of an ascending aortic aneurysm, the maximum blood velocity was found to be 1.6 times lower than in the healthy aorta. The aneurysm-based model demonstrates a 45% greater wall displacement, while the oscillatory shear index decreased by 30% compared to healthy aortic results.

Indexed as

Aortic AneurysmModels, CardiovascularAortaBlood Flow VelocityHemodynamicsHumansStress, MechanicalAscending aortic aneurysmblood flowcomputational fluid dynamics (CFD)finite element method (FEM)SimVascular

Identifiers

PMID34806632
PMCPMC8842780
OpenAlexW3214151239

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.