ArticleAnalytical chemistry2021
Smartphone-Based Janus Micromotors Strategy for Motion-Based Detection of Glutathione.
Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 45 citations in OpenAlex.
- Smartphone-based biosensing: a review of optical imaging, microfluidic integration, and AI-enhanced analysis.Mikrochimica acta · 2025Review
- Technology Roadmap of Micro/Nanorobots.ACS nano · 2025Review
- Micromotors Meet Collective (Bio)sensing: The Asset Behind the Assay.Analytical chemistry · 2025Review
- Novel methods for the detection of glutathione by surface-enhanced Raman scattering: A perspective review.Heliyon · 2025Review
- Raspberry-shaped ZIF-8/Au nanozymes with excellent peroxidase-like activity for simple and visual detection of glutathione.Analytical and bioanalytical chemistry · 2024Article
- Molecular Memory Micromotors for Fast Snake Venom Toxin Dynamic Detection.Analytical chemistry · 2024Article
- Untethered Micro/Nanorobots for Remote Sensing: Toward Intelligent Platform.Nano-micro letters · 2023Review
- Emerging Roles of Microrobots for Enhancing the Sensitivity of Biosensors.Nanomaterials (Basel, Switzerland) · 2023Review
- Micro-/nanoscale robotics for chemical and biological sensing.Lab on a chip · 2023Review
- Electrokinetic Active Particles for Motion-Based Biomolecule Detection.Nano letters · 2023Article
- Tailoring Functional Micromotors for Sensing.Research (Washington, D.C.) · 2023Article
- Analyte Sensing with Catalytic Micromotors.Biosensors · 2022Review
- Application of Janus Particles in Point-of-Care Testing.Biosensors · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herein, we describe a Janus micromotor smartphone platform for the motion-based detection of glutathione. The system compromises a universal three-dimensional (3D)-printed platform to hold a commercial smartphone, which is equipped with an external magnification optical lens (20-400×) directly attached to the camera, an adjustable sample holder to accommodate a glass slide, and a light-emitting diode (LED) source. The presence of glutathione in peroxide-rich sample media results in the decrease in the speed of 20 μm graphene-wrapped/PtNPs Janus micromotors due to poisoning of the catalytic layer by a thiol bond formation. The speed can be correlated with the concentration of glutathione, achieving a limit of detection of 0.90 μM, with percent recoveries and excellent selectivity under the presence of interfering amino acids and proteins. Naked-eye visualization of the speed decrease allows for the design of a test strip for fast glutathione detection (30 s), avoiding previous amplification strategies or sample preparation steps. The concept can be extended to other micromotor approaches relying on fluorescence or colorimetric detection for future multiplexed schemes.
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Registered trials
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