Evidence map›Paper›PMID 34806301›Full record

ArticleInternational journal of laboratory hematology2022

Impact of COVID-19 pandemic on the quality of test output in haemostasis laboratories.

Ryanne A Arisz, Piet Meijer, Nathalie C V Péquériaux, Sjef J van de Leur, Michaël V Lukens, Moniek P M de Maat, Martine J Hollestelle

Open access · bronzeAbstract read
In one paragraph

Article in International journal of laboratory hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Ryanne A AriszDepartment of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Piet MeijerECAT Foundation (External quality Control for Assays and Tests), Voorschoten, Netherlands.
Nathalie C V PéquériauxDepartment of Clinical Chemistry and Hematology, Jeroen Bosch Hospital, 's-Hertogenbosch, Netherlands.
Sjef J van de LeurDepartment of Clinical Chemistry, Isala Hospital, Zwolle, Netherlands.
Michaël V LukensDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Moniek P M de MaatDepartment of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0001-7749-334X
Martine J HollestelleECAT Foundation (External quality Control for Assays and Tests), Voorschoten, Netherlands.ORCID https://orcid.org/0000-0001-5672-3775
ACT Foundation · USErasmus MC · NLIsala · NLJeroen Bosch Ziekenhuis · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe high incidence of thrombotic events in patients with COVID-19 affects health care worldwide and results in an increased workload in haemostasis laboratories due to more frequent testing of D-dimer, haemostatic parameters and anti-Xa tests. However, the impact of this increase in assay requests on the quality of performance in haemostasis laboratories remains unclear. In this study, the impact of the COVID-19 pandemic on the quality of performance and management of haemostasis laboratories was evaluated.

methodsThe impact on the quality of performance was studied using external quality assessment data from 2019 to 2020 derived from ECAT surveys. A questionnaire was sent to Dutch haemostasis laboratories to identify challenges and management strategies. Furthermore, the number of assays performed in 2019 and 2020 was supplied by four Dutch hospitals, located in regions with different disease incidence.

resultsNo differences in response rate nor the quality of the measurements were observed between the EQA surveys in 2019 and 2020. The questionnaire results showed a large increase of >25% in the number of test requests for anti-Xa, D-dimer and fibrinogen assays in 2020 compared to 2019. Extreme peaks in test requests were also observed in the four evaluated hospitals. Additionally, 84% of the respondents indicated that they had experienced increased work pressure, and increased sick leave was observed in 71% of the participating laboratories.

conclusionsThe enormous increase in test requests, especially for D-dimer assays and anti-Xa activity, did not affect the quality of performance within haemostatic laboratories during the COVID-19 pandemic.

Indexed as

COVID-19Blood Coagulation TestsHemostasisHumansLaboratoriesPandemicsQuality Assurance, Health CareCoagulationCOVID-19LaboratoriesQuality controlTesting performance

Identifiers

PMID34806301
PMCPMC9011814
OpenAlexW3216906023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.