Evidence map›Paper›PMID 34806141›Full record

ArticleMolecular biology reports2022

Curcumin induces apoptosis through caspase dependent pathway in human colon carcinoma cells.

Gülçin Yavuz Türel, Nilüfer Şahin Calapoğlu, Dilek Bayram, Meltem Özgöçmen, Vehbi Atahan Toğay, Eda Evgen Tülüceoğlu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gülçin Yavuz TürelDepartment of Medical Biology, Faculty of Medicine, Süleyman Demirel University, Çünür, 32260, Isparta, Turkey. gulcinturel@sdu.edu.tr.ORCID http://orcid.org/0000-0001-9481-4475
Nilüfer Şahin CalapoğluDepartment of Medical Biology, Faculty of Medicine, Süleyman Demirel University, Çünür, 32260, Isparta, Turkey.ORCID http://orcid.org/0000-0002-7376-1607
Dilek BayramDepartment of Histology and Embriology, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey.ORCID http://orcid.org/0000-0003-3568-2673
Meltem ÖzgöçmenDepartment of Histology and Embriology, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey.ORCID http://orcid.org/0000-0003-3190-4486
Vehbi Atahan ToğayDepartment of Medical Biology, Faculty of Medicine, Süleyman Demirel University, Çünür, 32260, Isparta, Turkey.ORCID http://orcid.org/0000-0003-4722-3845
Eda Evgen TülüceoğluDepartment of Medical Biology, Faculty of Medicine, Süleyman Demirel University, Çünür, 32260, Isparta, Turkey.ORCID http://orcid.org/0000-0001-8668-2038
Süleyman Demirel University · TR

Funding

Süleyman Demirel Üniversitesi 4693-D2-16
6 · The paper itself

Abstract

backgroundWe investigated the apoptotic effects of curcumin in the colon carcinoma cell line SW480. METHODS AND

resultsCells were treated with 40-200 μM curcumin for 24, 48, and 72 h, and the IC

conclusionsThese results suggest that curcumin may be a potential protective or treatment agent against colon cancer; however, further studies on curcumin-rich diets and curcumin bioavailability are required.

Indexed as

ApoptosisCarcinomaCaspase 3Caspase 8CaspasesCell Line, TumorCell ProliferationColonColonic NeoplasmsCurcuminHumansCASP3 protein, humanCASP8 protein, humanCaspase 3Caspase 8CaspasesCurcuminApoptosisCaspase 3Caspase 8CurcuminSW480

Identifiers

PMID34806141
OpenAlexW3215555214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.