Evidence map›Paper›PMID 34806135›Full record

ArticleCurrent medical science2022

Trends of Ten Leading Causes of Death in Head and Neck Squamous Cell Carcinoma.

Wen-Hui Liu, Yi-Nan Lu, Mei-Ting Sun, De-Heng Nie, Fu-Jun Han

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Article in Current medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Wen-Hui Liu *Cancer Center, The First Hospital of Jilin University, Changchun, 130021, China.
Yi-Nan Lu *College of Computer Science and Technology, Jilin University, Changchun, 130021, China.
Mei-Ting SunCancer Center, The First Hospital of Jilin University, Changchun, 130021, China.
De-Heng NieCancer Center, The First Hospital of Jilin University, Changchun, 130021, China.
Fu-Jun HanCancer Center, The First Hospital of Jilin University, Changchun, 130021, China. fujunhan@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn understanding of the leading causes of death in patients with head and neck squamous cell carcinoma (HNSCC) would be helpful to inform doctors, patients, and healthcare providers on disease management. This study aimed to comprehensively study the leading causes of death in these survivors.

methodsWe investigated the trends of risk factors for major causes of death in patients with HNSCC. Causes of death in HNSCC were obtained from the Surveillance, Epidemiology, and End Results registries. We characterized trends in the 5-year cumulative mortality as well as risk factors associated with the ten leading causes of death.

resultsAmong 48 297 deaths identified, the ten leading causes were as follows: HNSCC, heart disease, lung cancer, chronic obstructive pulmonary disease (COPD), cerebrovascular disease, pneumonia & influenza, accidents & adverse effects, esophagus cancer, chronic liver diseases, and septicemia. Non-HNSCC deaths surpassed HNSCC deaths 4 years after cancer diagnosis. There was a significant decline in the 5-year cumulative mortality from HNSCC, heart disease, lung cancer, COPD, cerebrovascular disease, and esophagus cancer. The risks of mortality from the ten leading causes varied with patient characteristics.

conclusionOur findings provide a useful picture of mortality patterns in HNSCC survivors, which might help when planning personalized HNSCC care.

Indexed as

AdultAgedCause of DeathCerebrovascular DisordersComorbidityFemaleHumansLung DiseasesMaleMiddle AgedPyrenesRegistriesRisk FactorsSquamous Cell Carcinoma of Head and NeckCoMoCAT compoundPyrenescause of deathhead and neckheart diseasesquamous cell carcinomatrend

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.