Evidence map›Paper›PMID 34806074›Full record

ArticleClinical nutrition open science2021

Assessment of anorexia and weight loss during the infection and recovery period of patients with coronavirus disease 2019 (COVID-19).

Masoumeh Khalighi Sikaroudi, Sanaz Rezaei Zonooz, Zohreh Ebrahimi, Hanieh Jebraili, Farnaz Farsi, Atefeh Talebi, Mohsen Masoodi

Open access · goldAbstract read
In one paragraph

Article in Clinical nutrition open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Masoumeh Khalighi SikaroudiDepartment of Health Sciences and Nutrition, Tehran University of Medical Sciences, Tehran, Iran.
Sanaz Rezaei ZonoozDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Zohreh EbrahimiDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Hanieh JebrailiDepartment of Health Sciences and Nutrition, Tehran University of Medical Sciences, Tehran, Iran.
Farnaz FarsiColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Atefeh TalebiColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mohsen MasoodiColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with coronavirus disease 2019 (COVID-19) can present anorexia and weight loss due to their symptoms and eating disorder which can lead to immune system weakness and increase the duration of recovery time. We aim to assess the severity and duration of anorexia and weight loss within the infection and recovery period in these patients.

methodWe retrospectively identified 233 COVID-19 patients (older than 18 years) were admitted to the Rasoul-e Akram Hospital, from August to December 2020. Their medical records were reviewed by researchers. Then, patients who had inclusion criteria were asked about duration and severity of anorexia, and also weight alternation during the infection and after the recovery period.

resultAnalyzed data were collected from 233 COVID-19 patients showed the mean duration of anorexia was 7.08 ± 10.41 days with a significant loss of appetite (- 75.55 ± 88.09, P-value < 0.001) at the period of anorexia compare to appetite improvement. Also, results demonstrated patients, especially males and severe illness subjects, significantly lost weight (P-value <0.001).Conclusion: anorexia and weight loss occur in people infected with the coronavirus and may affect the recovery process of these patients by reducing their food intake. The underlying mechanisms of SARS-CoV-2 related to interaction to the gastrointestinal tract and development of anorexia in these patients need to clarify in future studies.

Indexed as

AnorexiaARDS, acute respiratory distress syndromeBMI, Body mass indexCOPD, chronic obstructive pulmonary diseaseCOVID-19COVID-19, Coronavirus disease 2019GI, GastrointestinalHADs, Hospital Anxiety and Depression ScalesICU, intensive care unitIgG, Immunoglobulin GIgM, Immunoglobulin MMERS-CoV, Middle East respiratory syndrome coronavirusPCR, Polymerase chain reactionPHEIC, public health emergency of international concernRNA, Ribonucleic acidSARS-CoV-2SARS-CoV-2, severe acute respiratory syndrome coronavirus 2SD, standard deviationVASs, visual analog scalesWeight lossWHO, World Health Organization

Identifiers

PMID34806074
PMCPMC8590500
OpenAlexW3211437651

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.