Evidence map›Paper›PMID 34806006›Full record

ArticleJAC-antimicrobial resistance2021

Reduced transmission of

Alessandra Micozzi, Giovanni Manfredi Assanto, Laura Cesini, Clara Minotti, Claudio Cartoni, Saveria Capria, Giulia Ciotti, Danilo Alunni Fegatelli, Livia Donzelli, Maurizio Martelli and 1 more

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Antibiotic resistance associated with the COVID-19 pandemic: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Plant-Origin Components: New Players to Combat Antibiotic Resistance inInternational journal of molecular sciences · 2024
    Review
  7. The epidemiology of multidrug-resistant organisms in persons diagnosed with cancer in Norway, 2008-2018: expanding surveillance using existing laboratory and register data.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  8. Epidemiology and outcomes of carbapenem-resistantFrontiers in microbiology · 2024
    Article
  9. Article
  10. Article
  11. Antibiotic Heteroresistance inInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alessandra MicozziDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-1358-6680
Giovanni Manfredi AssantoDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Laura CesiniDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Clara MinottiDepartment of Haematology, Oncology and Dermatology, Azienda Policlinico Umberto I, Rome, Italy.
Claudio CartoniDepartment of Haematology, Oncology and Dermatology, Azienda Policlinico Umberto I, Rome, Italy.
Saveria CapriaDepartment of Haematology, Oncology and Dermatology, Azienda Policlinico Umberto I, Rome, Italy.
Giulia CiottiDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Danilo Alunni FegatelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Livia DonzelliDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Maurizio MartelliDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Giuseppe GentileDepartment of Translational and Precision Medicine, Haematology, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDuring the lockdown that started in Italy on 10 March 2020 to address the COVID-19 pandemic, aggressive procedures were implemented to prevent SARS-CoV-2 transmission in SARS-CoV-2-negative patients with haematological malignancies. These efforts progressively reduced PATIENTS AND

methodsWe analysed KPC-KP spread among 123 patients with haematological malignancies, hospitalized between March and August 2020, who were managed using measures against COVID-19. Their outcomes were compared with those of 80 patients hospitalized during the preceding 4 months (November 2019-February 2020).

resultsDuring March-August 2020, 15.5% of hospitalized patients were KPC-KP positive, compared with 52.5% in November 2019-February 2020 (

conclusionsAggressive strategies to prevent SARS-CoV-2 transmission were applied to all hospitalized patients, characterized by high levels of KPC-KP endemicity and nosocomial transmission. Such measures prevented SARS-CoV-2 infection acquisition and KPC-KP horizontal transmission. Reduced KPC-KP spread, fewer associated clinical complications and decreased ceftazidime/avibactam consumption represented unexpected 'collateral benefits' of strategies to prevent COVID-19.

Identifiers

PMID34806006
PMCPMC8599827
OpenAlexW3211542207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.