ArticleBrain communications2021
Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide.
Open access · goldAbstract read
In one paragraph
Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis.Journal of the American Heart Association · 2022Pooled it
- Resting-State Activity and Connectivity of Dopaminergic Key Areas and Outcome After a Severe Stroke.The European journal of neuroscience · 2026Article
- Associations between contralesional neuroplasticity and motor impairment through deep learning-derived MRI regional brain age in chronic stroke (ENIGMA): a multicohort, retrospective, observational study.The Lancet. Digital health · 2026Observational
- Collaborative AI for precision neurorehabilitation: a roadmap.Journal of neuroengineering and rehabilitation · 2025Review
- Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke.Neurological research and practice · 2025Article
- Secondary thalamic dysfunction underlies abnormal large-scale neural dynamics in chronic stroke.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Severe motor impairment is associated with lower contralesional brain age in chronic stroke.medRxiv : the preprint server for health sciences · 2024Article
- Modulation of the Association Between Corticospinal Tract Damage and Outcome After Stroke by White Matter Hyperintensities.Neurology · 2024Article
- Dopaminergic mesolimbic structural reserve is positively linked to better outcome after severe stroke.Brain communications · 2024Article
- White matter hyperintensities modify relationships between corticospinal tract damage and motor outcomes after stroke.medRxiv : the preprint server for health sciences · 2023Article
- Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke.Neurology · 2023Observational
- SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry.Science advances · 2023Article
- Modulation of neural co-firing to enhance network transmission and improve motor function after stroke.Neuron · 2022Review
- A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms.Scientific data · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
72 authors at 20 institutions in 13 countries.
Sook-Lei LiewChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0001-5935-4215
Artemis Zavaliangos-PetropuluNeuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA.
Nicolas SchweighoferBiokinesiology and Physical Therapy, Ostrow School of Medicine, University of Southern California, Los Angeles, CA, USA.
Neda JahanshadImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
Catherine E LangDepartments of Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Keith R LohseDepartment of Health and Kinesiology, University of Utah, Salt Lake City, UT, USA.
Nerisa BanajLaboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Giuseppe BarisanoNeuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0001-5598-1369
Lee A BaughBasic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, USA.
Anup K BhattacharyaMallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.ORCID https://orcid.org/0000-0001-8145-8176
Bavrina BigjahanDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Michael R BorichDepartment of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Lara A BoydDepartment of Physical Therapy & the Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.ORCID https://orcid.org/0000-0002-2828-4549
Amy BrodtmannFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia.
Cathrin M BuetefischDepartment of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Winston D ByblowDepartment of Exercise Sciences and Centre for Brain Research, University of Auckland, Auckland, New Zealand.
Jessica M CassidyAllied Health Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID https://orcid.org/0000-0003-3469-0399
Charalambos C CharalambousDepartment of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.ORCID https://orcid.org/0000-0002-1547-1839
Valentina CiulloLaboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Adriana B ConfortoHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Richard C CraddockDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Adrienne N DulaDepartment of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Natalia EgorovaFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia.ORCID https://orcid.org/0000-0002-9244-2900
Wuwei FengDepartment of Health Sciences & Research, Medical University of South Carolina, Charleston, SC, USA.
Kelene A FerchoCivil Aerospace Medical Institute, US Federal Aviation Administration, Oklahoma City, OK, USA.
Chris M GregoryDepartment of Health Sciences & Research, Medical University of South Carolina, Charleston, SC, USA.
Colleen A HanlonCancer Biology, Wake Forest School of Medicine, Winston Salem, NC, USA.
Kathryn S HaywardFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia.ORCID https://orcid.org/0000-0001-5240-3264
Jess A HolguinChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Brenton HordacreInnovation, IMPlementation and Clinical Translation (IIMPACT) in Health, Allied Health and Human Performance, University of South Australia, Adelaide, SA, Australia.ORCID https://orcid.org/0000-0002-7129-6684
Darryl H HwangDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-1111-9176
Steven A KautzDepartment of Health Sciences & Research, Medical University of South Carolina, Charleston, SC, USA.
Mohamed Salah KhlifFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia.
Bokkyu KimDepartment of Physical Therapy Education, College of Health Professions, SUNY Upstate Medical University, Syracuse, NY, USA.
Hosung KimKeck School of Medicine, Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA.
Amy KuceyeskiDepartment of Radiology, Weill Cornell Medicine, New York, NY, USA.
Bethany LoChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Jingchun LiuDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
David LinCenter for Neurotechnology and Neurorecovery, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6575-9849
Martin LotzeDepartment of Diagnostic Radiology, University Medicine Greifswald, Greifswald, Germany.ORCID https://orcid.org/0000-0003-4519-4956
Bradley J MacIntoshHurvitz Brain Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
John L MargetisChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Feroze B MohamedJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Jan Egil NordvikCatoSenteret Rehabilitation Center, Son, Norway.ORCID https://orcid.org/0000-0003-0981-648X
Matthew A PetoeBionics Institute, Melbourne, VIC, Australia.
Fabrizio PirasLaboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Sharmila RajuDepartment of Neurology, New York University Langone, New York, NY, USA.ORCID https://orcid.org/0000-0001-5456-5056
Ander Ramos-MurguialdayTECNALIA, Basque Research and Technology Alliance (BRTA), Health Division, San Sebastian Donostia, Spain.
Kate P RevillFacility for Education and Research in Neuroscience, Emory University, Atlanta, GA, USA.
Pamela RobertsChan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, CA, USA.
Andrew D RobertsonCanadian Partnership for Stroke Recovery, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-9095-9877
Heidi M SchambraDepartment of Neurology, New York University Langone, New York, NY, USA.
Na Jin SeoDepartment of Health Sciences & Research, Medical University of South Carolina, Charleston, SC, USA.ORCID https://orcid.org/0000-0001-6446-5905
Mark S ShiroishiImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
Surjo R SoekadarClinical Neurotechnology Laboratory, Department of Psychiatry and Psychotherapy, Charité - University Medicine Berlin, Berlin, Germany.
Gianfranco SpallettaLaboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Cathy M StinearDepartment of Medicine, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-9404-1959
Anisha SuriDepartment of Electrical and Computer Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Wai Kwong TangDepartment of Psychiatry, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong, China.
Gregory T ThielmanDepartment of Physical Therapy and Neuroscience, University of the Sciences, Philadelphia, PA, USA.
Vincent N ThijsFlorey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia.
Daniela VecchioLaboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Nick S WardUCL Queen Square Institute of Neurology, London, UK.
Lars T WestlyeDepartment of Psychology, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-8644-956X
Carolee J WinsteinBiokinesiology and Physical Therapy, Ostrow School of Medicine, University of Southern California, Los Angeles, CA, USA.
George F WittenbergDepartment of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Kristin A WongDepartment of Physical Medicine & Rehabilitation, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Chunshui YuDepartment of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Steven L WolfDivision of Physical Therapy Education, Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Steven C CramerCalifornia Rehabilitation Institute, Los Angeles, CA, USA.
Paul M ThompsonImaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
ENIGMA Stroke Recovery Working Group
University of Southern California · USMedical University of South Carolina · USThe University of Melbourne · AUEmory University · USFondazione Santa Lucia · ITNYU Langone Health · USBionics Institute · AUSunnybrook Health Science Centre · CAThe University of Texas at Austin · USTianjin Medical University General Hospital · CNUniversity of Auckland · NZUniversity of California, Los Angeles · USBaylor College of Medicine · USFederal Aviation Administration · USHospital Israelita Albert Einstein · BRNational Hospital for Neurology and Neurosurgery · GBOslo University Hospital · NOThomas Jefferson University · USUniversity of British Columbia · CAUniversity of North Carolina at Chapel Hill · US
Funding
Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5MCorticoreticulospinal Tract Reorganization After StrokeR01NS110696 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHAMBRA, HEIDI · 2019 to 2023
$3.2MSupplement to Effects of global brain health on sensorimotor recovery after strokeR01NS115845 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LIEW, SOOK-LEI · 2020 to 2024
$3.2MCustomized cortical stimulation therapy in the rehabilitation of stroke patientsR01NS090677 · NINDS · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2015 to 2018
$3.0MBig Data Neuroimaging to Predict Motor Behavior After StrokeK01HD091283 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LIEW, SOOK-LEI · 2017 to 2020
$802kBrain Network Connectivity Measures in Early Stroke RehabilitationR00HD091375 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CASSIDY, JESSICA M · 2019 to 2021
$550kOptimizing sensori-motor training post-strokeR56NS100528 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SCHWEIGHOFER, NICOLAS · 2017 to 2017
$483kReorganizing motor cortex in stroke patient through Hebbian-type stimulationR21HD067906 · NICHD · EMORY UNIVERSITY · PI BUETEFISCH, CATHRIN M · 2011 to 2012
$464kNICHD NIH HHS K01 HD091283NICHD NIH HHS R00 HD091375NICHD NIH HHS R21 HD067906NIGMS NIH HHS P20 GM109040NINDS NIH HHS L30 NS093611NINDS NIH HHS R01 NS090677NINDS NIH HHS R01 NS110696NINDS NIH HHS R01 NS115845NINDS NIH HHS R56 NS100528RRD VA I01 RX001935RRD VA IK6 RX003075
Abstract
Up to two-thirds of stroke survivors experience persistent sensorimotor impairments. Recovery relies on the integrity of spared brain areas to compensate for damaged tissue. Deep grey matter structures play a critical role in the control and regulation of sensorimotor circuits. The goal of this work is to identify associations between volumes of spared subcortical nuclei and sensorimotor behaviour at different timepoints after stroke. We pooled high-resolution T
Indexed as
MRIrehabilitationsensorimotor behaviourstrokesubcortical volumes
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