Evidence map›Paper›PMID 34805995›Full record

ArticleBrain communications2021

Increased scale-free and aperiodic neural activity during sensorimotor integration-a novel facet in Tourette syndrome.

Nico Adelhöfer, Theresa Paulus, Moritz Mückschel, Tobias Bäumer, Annet Bluschke, Adam Takacs, Eszter Tóth-Fáber, Zsanett Tárnok, Veit Roessner, Anne Weissbach and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Nico AdelhöferCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.
Theresa PaulusInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Moritz MückschelCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.
Tobias BäumerInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Annet BluschkeCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.
Adam TakacsCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.
Eszter Tóth-FáberDoctoral School of Psychology, ELTE Eötvös Loránd University, 1064 Budapest, Hungary.
Zsanett TárnokVadaskert Child and Adolescent Psychiatry Hospital and Outpatient Clinic, 1021 Budapest, Hungary.
Veit RoessnerCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.
Anne WeissbachInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.
Alexander MünchauInstitute of Systems Motor Science, University of Lübeck, 23562 Lübeck, Germany.ORCID https://orcid.org/0000-0002-3219-2284
Christian BesteCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01069 Dresden, Germany.ORCID https://orcid.org/0000-0002-2989-9561
Technische Universität Dresden · DEUniversity of Lübeck · DEEötvös Loránd University · HUShandong Normal University · CNVadaskert Alapítvány a Gyermekek Lelki Egészségéért · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourette syndrome is a common neurodevelopmental disorder defined by multiple motor and phonic tics. Tics in Tourette syndrome resemble spontaneously occurring movements in healthy controls and are therefore sometimes difficult to distinguish from these. Tics may in fact be mis-interpreted as a meaningful action, i.e. a signal with social content, whereas they lack such information and could be conceived a surplus of action or 'motor noise'. These and other considerations have led to a 'neural noise account' of Tourette syndrome suggesting that the processing of neural noise and adaptation of the signal-to-noise ratio during information processing is relevant for the understanding of Tourette syndrome. So far, there is no direct evidence for this. Here, we tested the 'neural noise account' examining 1/

Indexed as

cognitiondopaminesignal-to-noise ratioTourette syndrome

Identifiers

PMID34805995
PMCPMC8599001
OpenAlexW3210978246

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.