ArticleBrain communications2021
Posterior cortical atrophy phenotypic heterogeneity revealed by decoding
Abstract read
In one paragraph
Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Improving the clinical trial landscape for patients with atypical variants of Alzheimer's disease: a call to action.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Functional network contributions to longitudinal tau spread in Posterior Cortical Atrophy.NPJ dementia · 2026Article
- Disrupted brain topological network and its association with clinical features in posterior cortical atrophy.Brain communications · 2026Article
- Posterior Cortical Atrophy: Altered Language Processing System Connectivity and Its Implications on Language Comprehension and Production.Brain sciences · 2025Article
- Phenotype-specific metabolic patterns in Posterior cortical atrophy and early-onset typical Alzheimer's disease.Annals of nuclear medicine · 2025Article
- Baseline multimodal imaging to predict longitudinal clinical decline in atypical Alzheimer's disease.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Graded Multidimensional Clinical and Radiologic Variation in Patients With Alzheimer Disease and Posterior Cortical Atrophy.Neurology · 2024Observational
- Decomposed FDG PET-based phenotypic heterogeneity predicting clinical prognosis and decision-making in temporal lobe epilepsy patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases.Brain : a journal of neurology · 2024Article
- Prosopagnosia: face blindness and its association with neurological disorders.Brain communications · 2024Article
- Assessing network degeneration and phenotypic heterogeneity in genetic frontotemporal lobar degeneration by decoding FDG-PET.NeuroImage. Clinical · 2024Article
- Deciphering the clinico-radiological heterogeneity of dysexecutive Alzheimer's disease.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Diagnosis and Management of Posterior Cortical Atrophy.Current treatment options in neurology · 2023Review
- Phenotypic subtypes of progressive dysexecutive syndrome due to Alzheimer's disease: a series of clinical cases.Journal of neurology · 2022Article
- Posterior cortical atrophy: Primary occipital variant.European journal of neurology · 2022Article
- Alzheimer's research-breakthrough or breakdown?Brain communications · 2021Article
- Homonymous hemianopia in posterior cortical atrophy: right-left asymmetry, progression over time and relationship to the classical neuropsychological deficits.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Ryan A TownleyDepartment of Neurology, University of Kansas Medical Center, Kansas City, KS 66160, USA.ORCID https://orcid.org/0000-0002-3566-3969
Hugo BothaDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-4390-685X
Jonathan Graff-RadfordDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-2770-0691
Jennifer WhitwellDepartment of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-4831-1276
Bradley F BoeveDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-4153-8187
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55902, USA.
Julie A FieldsDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55902, USA.
Daniel A DrubachDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Rodolfo SavicaDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Ronald C PetersenDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Matthew L SenjemInformation Technology Radiology, Mayo Clinic, Rochester, MN 55905, USA.
David S KnopmanDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Val J LoweDepartment of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Clifford R JackDepartment of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0001-7916-622X
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0003-2930-8634
David T JonesDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Funding
SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6MTHE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9MPREDICTING ALZHEIMERS DISEASE WITH MAGNETIC RESONANCER01AG011378 · NIA · MAYO CLINIC ROCHESTER · PI JACK, CLIFFORD R. · 1993 to 2017
$12.1MRochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5MUnderstanding the role of TDP-43 in Alzheimers disease and FTLDR01AG037491 · NIA · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2010 to 2024
$6.5MValidating the New Criteria for Preclinical Alzheimer's diseaseR01AG041851 · NIA · MAYO CLINIC ROCHESTER · PI JACK, CLIFFORD R., KNOPMAN, DAVID S · 2012 to 2021
$6.3MMolecular and structural imaging in atypical Alzheimer's disease: a longitudinal studyR01AG050603 · NIA · MAYO CLINIC ROCHESTER · PI WHITWELL, JENNIFER LOUISE · 2016 to 2025
$5.9MDevelopment, Validation, and Application of an Imaging based CVD ScaleR01NS097495 · NINDS · MAYO CLINIC ROCHESTER · PI VEMURI, PRASHANTHI · 2016 to 2020
$2.9MAssessment of hyperphosphorylated tau PET binding in primary progressive aphasiaR21NS094684 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2016 to 2017
$417kNIA NIH HHS P50 AG016574NIA NIH HHS R01 AG011378NIA NIH HHS R01 AG034676NIA NIH HHS R01 AG037491NIA NIH HHS R01 AG041851NIA NIH HHS R01 AG050603NIA NIH HHS U01 AG006786NINDS NIH HHS R01 NS097495NINDS NIH HHS R21 NS094684
Abstract
Posterior cortical atrophy is a neurodegenerative syndrome with a heterogeneous clinical presentation due to variable involvement of the left, right, dorsal and ventral parts of the visual system, as well as inconsistent involvement of other cognitive domains and systems.
Indexed as
early-onset Alzheimer's diseaseeigenvectorsFDG-PETposterior cortical atrophytau PET
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.