Evidence map›Paper›PMID 34805966›Full record

ArticleBiosafety and health2021

Sirolimus combined with oseltamivir and corticosteroid treatment for a puerpera with severe pneumonia caused by 2009 pandemic H1N1: A case report.

Lijun Suo, Xiaofeng Yu, Yongfeng Hu, Hongyun Cao, Xiaohui Zou, Peiquan Wang, Tao Xu, Xiangzhi Zhou, Yexin Wu, Lili Ren and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosafety and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lijun SuoDepartment of Pulmonary and Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Xiaofeng YuZibo City Key Laboratory of Respiratory Infection and Clinical Microbiology & Zibo City Engineering Technology Research Center of Etiology Molecular Diagnosis, Zibo 255400, China.
Yongfeng HuNational Health Commission Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Hongyun CaoZibo City Key Laboratory of Respiratory Infection and Clinical Microbiology & Zibo City Engineering Technology Research Center of Etiology Molecular Diagnosis, Zibo 255400, China.
Xiaohui ZouDepartment of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Tsinghua University-Peking University Joint Center for Life Sciences, Beijing 100029, China.
Peiquan WangDepartment of Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Tao XuDepartment of Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Xiangzhi ZhouDepartment of Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Yexin WuDepartment of Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Lili RenNational Health Commission Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Bo LiuDepartment of Pulmonary and Critical Care Medicine, Zibo Municipal Hospital, Zibo 255400, China.
Bin CaoDepartment of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, Tsinghua University-Peking University Joint Center for Life Sciences, Beijing 100029, China.
Central Hospital of Zibo · CNCenter for Life Sciences · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe pneumonia in patients infected with the 2009 pandemic H1N1 (pH1N1) virus was partially attributed to excessive immune response. Anti-virus treatment for these patients was insufficient. Here we reported the therapy effect of sirolimus, an immunosuppressor, combined with oseltamivir and corticosteroid for a puerpera with severe pneumonia caused by pH1N1 virus. This patient has infected with the pH1N1 virus in late pregnancy, and antiviral therapy was not implemented timely. She developed severe pneumonia and ARDS rapidly and need receive a cesarean section on the 39

Indexed as

CorticosteroidH1N1OseltamivirPneumoniaPuerperaSirolimus

Identifiers

PMID34805966
PMCPMC8590738
OpenAlexW3211347339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.