ArticleKidney international reports2021
Birth Weight Is Associated With Kidney Size in Middle-Aged Women.
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Birthweight and Breastfeeding Shape Patterns of Biological Aging Across Adult Organs.Aging cell · 2026Article
- Multifetal Pregnancies in Women with CKD: Risk Assessment and Indications for Counseling.Kidney360 · 2026Article
- Sex and Gender Differences in Chronic Kidney Disease-Explained by the Brenner-Luyckx Concept of Hyperfiltration.Journal of clinical medicine · 2026Review
- The impact of visual and hearing impairments on the risk of arthritis among middle-aged and older Chinese adults (2011-2015): the mediating role of depressive symptoms.BMC public health · 2025Article
- Modeling the genomic architecture of adiposity and anthropometrics across the lifespan.Nature communications · 2025Article
- Relationship between new-onset proteinuria and the volume of the non-donated kidney before and after donation in living kidney donors.Clinical and experimental nephrology · 2025Observational
- Chronic kidney disease and the global public health agenda: an international consensus.Nature reviews. Nephrology · 2024Review
- Impact of CT-determined low kidney volume on renal function decline: a propensity score-matched analysis.Insights into imaging · 2024Article
- Fetal growth restriction followed by very preterm birth is associated with smaller kidneys but preserved kidney function in adolescence.Pediatric nephrology (Berlin, Germany) · 2023Article
- From the Cradle to the Grave: The Life Cycle of Gender Disparities in Kidney Care.Kidney international reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLow birth weight (LBW) is associated with increased risk of kidney disease due to lower nephron endowment leading to hyperfiltration and subsequent nephron loss. Kidney size is commonly used as a proxy for nephron number. We compared kidney volume measured by magnetic resonance imaging (MRI) with measured glomerular filtration rate (mGFR) in adults with either normal birth weight (NBW) or low birth weight (LBW).
methodsHealthy individuals aged 42 to 52 years with LBW (1100-2300 g) and NBW (3500 -4000 g) were invited to participate. The GFR was measured using plasma clearance of iohexol. Kidney volume was measured on magnetic resonance images using axial T2 images and coronal T1 images with fat saturation without contrast enhancement; calculations were performed according to the ellipsoid formula π/6 × length × width × depth.
resultsWe included 102 individuals (54 LBW and 48 NBW). Total kidney volume was 302 ± 51 ml for female NBW vs 258 ± 48 ml for female LBW individuals (
conclusionHealthy female individuals born with LBW have smaller kidneys than healthy females born with NBW. The previously shown associations between LBW and lower mGFR in adult women might be explained by smaller kidney volume.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.