Evidence map›Paper›PMID 34805440›Full record

ArticleOpen forum infectious diseases2021

High Mortality During the Second Wave of the Coronavirus Disease 2019 (COVID-19) Pandemic in Uganda: Experience From a National Referral COVID-19 Treatment Unit.

Felix Bongomin, Brian Fleischer, Ronald Olum, Barbra Natukunda, Sarah Kiguli, Pauline Byakika-Kibwika, Joseph Baruch Baluku, Frederick Nelson Nakwagala

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Coinfection of COVID-19 and Tuberculosis in Uganda.The American journal of tropical medicine and hygiene · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felix BongominDepartment of Medical Microbiology & Immunology, Faculty of Medicine, Gulu University, Gulu, Uganda.ORCID https://orcid.org/0000-0003-4515-8517
Brian FleischerDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Ronald OlumDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.ORCID https://orcid.org/0000-0003-1289-0111
Barbra NatukundaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Sarah KiguliDepartment of Pediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Pauline Byakika-KibwikaDepartment of Medicine, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Joseph Baruch BalukuDivision of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda.
Frederick Nelson NakwagalaDepartment of Internal Medicine, Mulago National Referral Hospital, Kampala, Uganda.

Funding

Health Professions Education and training for strengthening the health system and services in UgandaR25TW011213 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KIGULI, SARAH · 2018 to 2022
$3.4M
FIC NIH HHS R25 TW011213
6 · The paper itself

Abstract

backgroundWe evaluated clinical outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the second wave of the pandemic in a national COVID-19 treatment unit (CTU) in Uganda.

methodsWe conducted a retrospective cohort study of COVID-19 patients hospitalized at the Mulago National Referral Hospital CTU between May 1 and July 11, 2021. We performed Kaplan-Meier analysis to evaluate all-cause in-hospital mortality.

resultsOf the 477 participants, 247 (52%) were female, 15 (3%) had received at least 1 dose of the COVID-19 vaccine, and 223 (46%) had at least 1 comorbidity. The median age was 52 (interquartile range, 41-65) years. More than 80% of the patients presented with severe (19%, n=91) or critical (66%, n=315) COVID-19 illness. Overall, 174 (37%) patients died. Predictors of all-cause in-hospital mortality were as follows; age ≥50 years (adjusted odds ratio [aOR], 1.9; 95% confidence interval [CI], 1.2-3.2;

conclusionsIn this cohort, where the majority of the patients presented with severe or critical illness, more than one third of the patients hospitalized with COVID-19 at a national CTU died of the illness.

Indexed as

COVID-19high-dependency unitmortalitysecond waveUganda

Identifiers

PMID34805440
PMCPMC8601041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.