Evidence map›Paper›PMID 34805439›Full record

ArticleOpen forum infectious diseases2021

Crushing and Splitting Direct-Acting Antivirals for Hepatitis C Virus Treatment: A Case Series and Literature Review.

Kristen Whelchel, Autumn D Zuckerman, David E Koren, Caroline Derrick, Jeannette Bouchard, Cody A Chastain

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristen WhelchelSpecialty Pharmacy Services, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0003-3393-7863
Autumn D ZuckermanSpecialty Pharmacy Services, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-8376-0691
David E KorenDepartment of Pharmacy Services, Temple University Health System, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6601-9893
Caroline DerrickDepartment of Infectious Disease, University of South Carolina, Columbia, South Carolina, USA.
Jeannette BouchardDepartment of Pharmacy, University of South Carolina, Columbia, South Carolina, USA.ORCID https://orcid.org/0000-0003-0626-9695
Cody A ChastainDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0001-6771-7397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited data exist regarding the use of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) in patients who are unable to swallow tablets. This case series describes HCV treatment in patients requiring tablet manipulation, providing evidence for safety and effectiveness of HCV DAA tablet manipulation.

Indexed as

chroniccrushingdeglutitiondirect-acting antiviralhepatitis Csplittingtablet

Identifiers

PMID34805439
PMCPMC8601046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.