Evidence map›Paper›PMID 34805285›Full record

ArticleFrontiers in molecular biosciences2021

Detection of Mosaic Variants in Mothers of MPS II Patients by Next Generation Sequencing.

Alice Brinckmann Oliveira Netto, Ana Carolina Brusius-Facchin, Sandra Leistner-Segal, Francyne Kubaski, Juliana Josahkian, Roberto Giugliani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alice Brinckmann Oliveira NettoLaboratory of Molecular Genetics, Medical Genetics Service, HCPA, Porto Alegre, Brazil.
Ana Carolina Brusius-FacchinLaboratory of Molecular Genetics, Medical Genetics Service, HCPA, Porto Alegre, Brazil.
Sandra Leistner-SegalLaboratory of Molecular Genetics, Medical Genetics Service, HCPA, Porto Alegre, Brazil.
Francyne KubaskiLaboratory of Molecular Genetics, Medical Genetics Service, HCPA, Porto Alegre, Brazil.
Juliana JosahkianPostgraduate Program in Genetics and Molecular Biology, UFRGS, Porto Alegre, Brazil.
Roberto GiuglianiLaboratory of Molecular Genetics, Medical Genetics Service, HCPA, Porto Alegre, Brazil.
Universidade Federal do Rio Grande do Sul · BRNational Institute on Population Medical Genetics · BRHospital Universitário de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucopolysaccharidosis type II is an X-linked lysosomal storage disorder caused by mutations in the

Indexed as

carrier detectionhunter syndromeIDS genemosaicismmucopolysaccharidosis type IInext-generation sequencingx-linked disease

Identifiers

PMID34805285
PMCPMC8602069
OpenAlexW3212414809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.