Evidence map›Paper›PMID 34805273›Full record

ReviewFrontiers in molecular biosciences2021

NcRNAs in Vascular and Valvular Intercellular Communication.

Benedikt Bartsch, Philip Roger Goody, Mohammed Rabiul Hosen, Denise Nehl, Neda Mohammadi, Andreas Zietzer, Philip Düsing, Alexander Pfeifer, Georg Nickenig, Felix Jansen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. RNA Pol II Assembly Affects ncRNA Expression.International journal of molecular sciences · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Benedikt BartschDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Philip Roger GoodyDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Mohammed Rabiul HosenDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Denise NehlDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Neda MohammadiInstitute of Pharmacology and Toxicology, University Hospital Bonn, Bonn, Germany.
Andreas ZietzerDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Philip DüsingDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Alexander PfeiferInstitute of Pharmacology and Toxicology, University Hospital Bonn, Bonn, Germany.
Georg NickenigDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
Felix JansenDepartment of Internal Medicine II, Heart Center Bonn, University Hospital Bonn, Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs have been shown to be important biomarkers and mediators of many different disease entities, including cardiovascular (CV) diseases like atherosclerosis, aneurysms, and valvulopathies. Growing evidence suggests a central role of ncRNAs as regulators of different pathological pathways involved in endothelial dysfunction, cardiovascular inflammation, cell differentiation, and calcification. This review will discuss the role of protein-bound and extracellular vesicular-bound ncRNAs as biomarkers of vascular and valvular diseases, their role as intercellular communicators, and regulators of disease pathways and also highlights possible treatment strategies.

Indexed as

aortic stenosisatherosclerosisendothelial dysfunctionncRNAncRNA therapy

Identifiers

PMID34805273
PMCPMC8602872
OpenAlexW3212877943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.