Evidence map›Paper›PMID 34804608›Full record

ArticleNeurology research international2021

Investigation of the Possible Correlation between Idiopathic Parkinson's Disease and Diabetes Mellitus in Egyptian Patients: A Pilot Study.

Afnan AwadAllah Elgnainy, Mohammad Ismail Hamed, Wael Osman Mohamed, Nagwa Ali Sabri

Registry-linked trialAbstract read
In one paragraph

Article in Neurology research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03685357 (Investigation of the Possible Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus in Egyptian Elderly Patients), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03685357 unknown statusnot on this map

Investigation of the Possible Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus in Egyptian Elderly Patients

TypeobservationalSponsorAin Shams UniversityRan2018 to 2020Enrolled120ConditionsObservation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Afnan AwadAllah ElgnainyDepartment of Clinical Pharmacy, Faculty of Pharmacy, Misr University for Science and Technology, Giza, Egypt.ORCID https://orcid.org/0000-0001-6788-8970
Mohammad Ismail HamedDepartment of Clinical Pharmacy, Faculty of Pharmacy, Misr University for Science and Technology, Giza, Egypt.
Wael Osman MohamedDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Nagwa Ali SabriDepartment of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the diabetes-Parkinson's disease (PD) linkage.

methodsThe investigators recorded the rapid eye movement sleep behavior disorder screening questionnaire (RBDSQ) score for 60 diabetic patients: 30 patients were treated with metformin-inclusive sulfonylurea and 30 patients were treated with sulphonylurea(s) monotherapy and matched with 30 controls. We evaluated blood glucose kinetics during a 75 g oral glucose tolerance test for (22) nondiabetic parkinsonian patients and (10) controls. The motor complications scores were recorded for all parkinsonian patients using the relevant parts of the Unified Parkinson's Disease Rating Scale (UPDRS) part IV.

resultsDiabetics recorded higher scores of RBDSQ than controls (

conclusionDiabetes mellitus and Parkinson's disease are linked, which raises concerns about either of them, probably increasing the risk of the other. This trial is registered with NCT03685357.

Identifiers

PMID34804608
PMCPMC8604607

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