ArticleVirus evolution2020
Genetic recombination in fast-spreading coxsackievirus A6 variants: a potential role in evolution and pathogenicity.
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Article in Virus evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
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Who cites it
24 citing papers in PubMed.
- Epidemiological Characteristics of Coxsackievirus A6 in Baotou, Inner Mongolia, China, 2023-2024.Viruses · 2026Article
- In Silico Saturation-Mutagenesis-Based Genomic Mutation Risk Assessment for Enterovirus B.Viruses · 2026Article
- Article
- Global distribution and evolution of nine major non-polio enteroviruses revealed by genomic data mining.Biochemistry and biophysics reports · 2026Article
- Serial passagingFrontiers in cellular and infection microbiology · 2026Article
- Coxsackievirus A6 was the predominant pathogen of hand, foot, and mouth disease with frequent recombination and mutations in Shandong Province, 2023.Virus evolution · 2026Article
- Temporal phylodynamics of Coxsackievirus A6 VP1 in Shenzhen (2022-2024).BMC infectious diseases · 2025Article
- Epidemiological, etiological, and serological characteristics of hand, foot, and mouth disease in Guizhou Province, Southwest China, from 2008 to 2023.PLoS neglected tropical diseases · 2025Article
- Transition of D3c branch and novel recombination events contribute to the diversity of Coxsackievirus A6 in Beijing, China, from 2019 to 2023.Virus evolution · 2025Article
- Genetic variation and evolutionary characteristics of Echovirus 11: new variant within genotype D5 associated with neonatal death found in China.Emerging microbes & infections · 2024Article
- Changing Epidemiology of Hand, Foot, and Mouth Disease Causative Agents and Contributing Factors.The American journal of tropical medicine and hygiene · 2024Review
- A review of the recombination events, mechanisms and consequences of Coxsackievirus A6.Infectious medicine · 2024Review
- Evolutionary Diversity of Coxsackievirus A6 Causing Severe Hand, Foot, and Mouth Disease - China, 2012-2023.China CDC weekly · 2024Article
- Synergetic association between coxsackievirus A16 genotype evolution and recombinant form shifts.Virus evolution · 2024Article
- Molecular evolutionary dynamics of enterovirus A71, coxsackievirus A16 and coxsackievirus A6 causing hand, foot and mouth disease in Thailand, 2000-2022.Scientific reports · 2023Article
- Molecular epidemiology and clinical characteristics of enteroviruses associated HFMD in Chengdu, China, 2013-2022.Virology journal · 2023Article
- Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model.Viruses · 2023Article
- Surveillance, epidemiology, and impact of the coronavirus disease 2019 interventions on the incidence of enterovirus infections in Nanchang, China, 2010-2022.Frontiers in microbiology · 2023Article
- Article
- Molecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study.Emerging microbes & infections · 2022Article
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Authors and funding
20 authors.
Yang SongWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.ORCID 0000-0002-7053-3836
Yong ZhangWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.ORCID 0000-0002-2692-5437
Zhenzhi HanWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Wen XuYunnan Center for Disease Control and Prevention, Kunming, Yunnan Province, China.
Jinbo XiaoWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Xianjun WangShandong Center for Disease Control and Prevention, Jinan, Shandong Province, China.
Jianxing WangShandong Center for Disease Control and Prevention, Jinan, Shandong Province, China.
Jianfang YangShanxi Center for Disease Control and Prevention, Taiyuan, Shanxi Province, China.
Qiuli YuHebei Center for Disease Control and Prevention, Shijiazhuang, Hebei Province, China.
Deshan YuGansu Center for Disease Control and Prevention, Lanzhou, Gansu Province, China.
Jianhua ChenGansu Center for Disease Control and Prevention, Lanzhou, Gansu Province, China.
Wei HuangChongqing Center for Disease Control and Prevention, Chongqing City, China.
Jie LiBeijing Center for Disease Control and Prevention, Beijing City, China.
Tong XieTianjin Center for Disease Control and Prevention, Tianjin City, China.
Huanhuan LuWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Tianjiao JiWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Qian YangWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Dongmei YanWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Shuangli ZhuWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Wenbo XuWHO WPRO Regional Polio Reference Laboratory, National Health Commission Key Laboratory for Medical Virology, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, No. 155, Changbai Road, Changping District, Beijing, 102206, China.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hand, foot, and mouth disease (HFMD) is a common global epidemic. From 2008 onwards, many HFMD outbreaks caused by coxsackievirus A6 (CV-A6) have been reported worldwide. Since 2013, with a dramatically increasing number of CV-A6-related HFMD cases, CV-A6 has become the predominant HFMD pathogen in mainland China. Phylogenetic analysis based on the
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Coxsackievirus A6evolutionary dynamicsfoot and mouth diseasegenetic recombinationhandpathogenicityphylogenywhole-genome analysis
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