Evidence map›Paper›PMID 34804570›Full record

ArticleRoyal Society open science2021

Redox-mediated carbon monoxide release from a manganese carbonyl-implications for physiological CO delivery by CO releasing moieties.

Jacob A Barrett, Zhi Li, John V Garcia, Emily Wein, Dongyun Zheng, Camden Hunt, Loc Ngo, Lior Sepunaru, Alexei V Iretskii, Peter C Ford

Erratum issuedAbstract read
In one paragraph

Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. CO prodrugs: A new scaffold of adamantane-fused norbornen-7-ones with tunable water solubility.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024
    Article
  5. Iron Porphyrin-mediated Production of Carbon Monoxide from Phenylpyruvic Acid: From Potential Therapeutic and Diagnostic Use to Physiological Implications.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jacob A BarrettDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-7522-5699
Zhi LiDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
John V GarciaDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
Emily WeinDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
Dongyun ZhengDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0003-0124-670X
Camden HuntDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.
Loc NgoDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0001-9476-5335
Lior SepunaruDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.ORCID 0000-0002-4716-5035
Alexei V IretskiiDepartment of Chemistry and Environmental Sciences, Lake Superior State University, Sault Sainte Marie, MI 49783, USA.ORCID 0000-0002-0226-5788
Peter C FordDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of hydrogen peroxide reactions with metal carbonyls have received little attention. Given reports that therapeutic levels of carbon monoxide are released in hypoxic tumour cells upon manganese carbonyls reactions with endogenous H

Indexed as

CO releasing moietyhydrogen peroxidemanganese carbonylredox reaction

Identifiers

PMID34804570
PMCPMC8580448

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.