Evidence map›Paper›PMID 34804426›Full record

ArticleIranian journal of basic medical sciences2021

Attenuation of tacrolimus induced oxidative stress, mitochondrial damage, and cell cycle arrest by

Kalaivani M K, Cordelia Mano John, Bhavana Jonnagaladda, Akila Kesavan, Sumathy Arockiasamy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kalaivani M KDepartment of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 6000116, India.
Cordelia Mano JohnDepartment of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 6000116, India.
Bhavana JonnagaladdaDepartment of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 6000116, India.
Akila KesavanDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, 600116, India.
Sumathy ArockiasamyDepartment of Biomedical Sciences, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai 6000116, India.
Sri Ramachandra Institute of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe protective effect of ethyl acetate fraction (EAF) of MATERIALS AND

methodsEthanolic root extract of

resultsTAC induced toxicity, leading to apoptosis and necrosis, was significantly reduced (

conclusionThus, these results provide sound evidence that EAF may be an effective adjuvant therapy to prevent nephrotoxicity induced by TAC.

Indexed as

ApoptosisBoerhavia diffusaCaspase 3Cell cycleHPLCNephrotoxicityQuercetinReactive oxygen species

Identifiers

PMID34804426
PMCPMC8591757
OpenAlexW3188796555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.