Evidence map›Paper›PMID 34804382›Full record

ReviewJournal of community hospital internal medicine perspectives2021

COVID-19 reinfection: the role of natural immunity, vaccines, and variants.

Bao Y Sciscent, Caroline D Eisele, Lisa Ho, Steven D King, Rohit Jain, Reshma R Golamari

Abstract readReview
In one paragraph

Review in Journal of community hospital internal medicine perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. ACS pharmacology & translational science · 2025
    Article
  4. Stuck in pandemic uncertainty: a review of the persistent effects of COVID-19 infection in immune-deficient people.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2024
    Review
  5. Article
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  12. Post-COVID-19 Agenda: Who controls the narrative?Archives of medical research · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bao Y SciscentThe Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, USA.
Caroline D EiseleThe Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, USA.
Lisa HoThe Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, USA.
Steven D KingThe Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, USA.
Rohit JainDepartment of Hospital Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Reshma R GolamariDepartment of Hospital Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-8842-9762

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical.

Indexed as

COVID-19COVID-19 immunityCOVID-19 vaccinationreinfectionSARS-CoV-2

Identifiers

PMID34804382
PMCPMC8604456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.