Evidence map›Paper›PMID 34804270›Full record

ArticleGastroenterology research2021

Outcomes of Non-Variceal Upper Gastrointestinal Bleed Stratified by Hospital Teaching Status: Insights From the National Inpatient Sample.

Jennifer C Asotibe, Hafeez Shaka, Emmanuel Akuna, Niveda Shekar, Hassam Shah, Marcelo Ramirez, Syed Ali Amir Sherazi, Katayoun Khoshbin, Hemant Mutneja, Bashar Attar

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jennifer C AsotibeDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Hafeez ShakaDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Emmanuel AkunaDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Niveda ShekarDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Hassam ShahDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Marcelo RamirezDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Syed Ali Amir SheraziDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Katayoun KhoshbinDepartment of Internal Medicine, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Hemant MutnejaDepartment of Gastroenterology, John H Stroger Hospital of Cook County, Chicago, IL, USA.
Bashar AttarDepartment of Gastroenterology, John H Stroger Hospital of Cook County, Chicago, IL, USA.
John H. Stroger, Jr. Hospital of Cook County · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-variceal upper gastrointestinal bleeding (NVUGIB) is a significant cause of mortality and morbidity in the USA. Currently, there are limited data on the inpatient outcomes of patients admitted with a diagnosis of NVUGIB stratified according to teaching hospital status. We analyzed data from the National Inpatient Sample (NIS) intending to evaluate these outcomes.

methodsWe queried the NIS 2016 and 2017 databases for NVUGIB hospitalizations by teaching hospital status. The primary outcome was inpatient mortality while secondary outcomes were rate of endoscopy for hemostasis, rate of early endoscopy (endoscopy in 1 day or less), mean time to endoscopy, rate of complications including acute kidney injury (AKI), acute respiratory failure (ARF), need for blood transfusion, development of sepsis, need for endotracheal intubation and mechanical ventilation as well as healthcare utilization.

resultsThere were over 71 million weighted discharges in the combined 2016 and 2017 NIS database. A total of 94,900 NVUGIB cases were identified with 63.4% admitted in teaching hospitals. The in-hospital mortality for patients admitted with an NVUGIB in teaching hospitals was 1.98% compared to 1.5% in non-teaching hospitals (adjusted odds ratio (aOR): 1.38, 95% confidence interval (CI): 1.08 - 1.77, P = 0.010) when adjusted for biodemographic and hospital characteristics as well as comorbidities. Patients admitted with a diagnosis of NVUGIB in teaching hospitals had a 10% adjusted increased odds of getting endoscopy for hemostasis (27.0% vs. 24.5%, aOR: 1.10, 95% CI: 1.02 - 1.19, P = 0.016) compared to patients in non-teaching hospitals. There was, however, no difference in early endoscopy between the two groups.

conclusionPatients admitted at teaching hospitals for an NVUGIB had worse outcomes during hospitalizations including mortality, median length of stay, and total hospital charges when compared to NVUGIB patients managed at non-teaching hospitals.

Indexed as

Length of stayMortalityNon-teaching hospitalNon-variceal upper gastrointestinal bleedingTeaching hospitalTotal hospital charges

Identifiers

PMID34804270
PMCPMC8577599
OpenAlexW3205888369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.