Evidence map›Paper›PMID 34804269›Full record

ArticleGastroenterology research2021

The Incidence of Endoscopic Retrograde Cholangiopancreatography-Related Complications in Patients With Liver Transplant: A Meta-Analysis and Systematic Review.

Mohammad Alomari, Laith Al Momani, Ahmed Alomari, Shrouq Khazaaleh, Asif Ali Hitawala, Amani Khasawneh, Prashanthi N Thota, Sreeni S Jonnalagadda, Madhusudhan R Sanaka

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In one paragraph

Article in Gastroenterology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Mohammad AlomariDepartment of Gastroenterology and Hepatology, Cleveland Clinic Florida, Weston, FL, USA.
Laith Al MomaniDepartment of Gastroenterology and Hepatology, University of Missouri - Kansas City, Kansas City, MO, USA.
Ahmed AlomariDepartment of Gastroenterology and Hepatology, University Hospitals Southampton NHS Trust, Southampton, England, UK.
Shrouq KhazaalehDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH, USA.
Asif Ali HitawalaDepartment of Internal Medicine, Cleveland Clinic Fairview Hospital, Cleveland, OH, USA.
Amani KhasawnehDepartment of Internal Medicine, King Abdullah University Hospital, Irbid, Jordan.
Prashanthi N ThotaDepartment of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic Foundation, Cleveland, OH, USA.
Sreeni S JonnalagaddaDepartment of Gastroenterology and Hepatology, University of Missouri - Kansas City, Kansas City, MO, USA.
Madhusudhan R SanakaDepartment of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic Foundation, Cleveland, OH, USA.
Cleveland Clinic · USUniversity of Missouri–Kansas City · USCleveland Clinic Florida · USKing Abdullah University Hospital · JOUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExisting literature on post-endoscopic retrograde cholangiopancreatography (ERCP) complications in patients with liver transplant remains scarce and largely inconsistent. We therefore aimed to systematically review and analyze the literature on complication rates associated with ERCP in patients with liver transplant.

methodsWe performed a comprehensive literature search in PubMed, PubMed Central, Embase, and ScienceDirect databases from inception through March 2020 to identify all the studies that evaluated post-ERCP complications in patients with liver transplant. Effect estimates from the individual studies were extracted and combined using the random effect, generic inverse variance method of DerSimonian and Laird, and a pooled odds ratio (OR) and event rates were calculated. Forest plots were generated, and publication bias was assessed for using conventional techniques.

resultsFourteen studies with a total of 1,787 patients were analyzed. In total, 3,192 ERCPs were performed on these patients. The pooled all-complication rate was 5.2% (95% confidence interval (CI): 0.035 - 0.075). Procedural complications analyzed included post-ERCP pancreatitis 3.4% (95% CI: 0.025 - 0.047), bleeding 1.1% (95% CI: 0.006 - 0.020), infections 0.2% (95% CI: 0.025 - 0.047), and cholangitis 0.8% (95% CI: 0.004 - 0.020). No cases of periprocedural death were reported. The pooled OR for post-ERCP pancreatitis in patients with liver transplant compared to patients without liver transplant was 1.289 (95% CI: 0.455 - 3.653, P = 0.633, I

conclusionPost-ERCP complication rates in liver transplant patients are comparable to the general population and hence, peri-procedural evaluation and management may follow the current standards of care in this patient population.

Indexed as

ComplicationsEndoscopic retrograde cholangiopancreatographyLiver transplantPancreatitis and cholangitis

Identifiers

PMID34804269
PMCPMC8577595
OpenAlexW3206730029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.