Evidence map›Paper›PMID 34804075›Full record

ArticleFrontiers in immunology2021

Tissue Specific Transcriptome Changes Upon Influenza A Virus Replication in the Duck.

Lee K Campbell, Ximena Fleming-Canepa, Robert G Webster, Katharine E Magor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Concurrent loss of ciliary genesRoyal Society open science · 2023
    Article
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  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lee K CampbellDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
Ximena Fleming-CanepaDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
Robert G WebsterDivision of Virology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Katharine E MagorDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CASt. Jude Children's Research Hospital · US

Funding

CIHR PJT 159442
6 · The paper itself

Abstract

Ducks are the natural host and reservoir of influenza A virus (IAV), and as such are permissive to viral replication while being unharmed by most strains. It is not known which mechanisms of viral control are globally regulated during infection, and which are specific to tissues during infection. Here we compare transcript expression from tissues from Pekin ducks infected with a recombinant H5N1 strain A/Vietnam 1203/04 (VN1203) or an H5N2 strain A/British Columbia 500/05 using RNA-sequencing analysis and aligning reads to the NCBI assembly ZJU1.0 of the domestic duck (

Indexed as

AnimalsDisease ReservoirsDucksFemaleGene Expression ProfilingGene Expression RegulationHost-Pathogen InteractionsHumansInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H5N2 SubtypeInfluenza, HumanInfluenza in BirdsMaleVirus Replicationduck (Anas platrhynchos)highly pathogenic avian influenzaproinflammatory cytokinesreservoir hostRNA-seq

Identifiers

PMID34804075
PMCPMC8602823
OpenAlexW3211811068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.