Evidence map›Paper›PMID 34804069›Full record

ArticleFrontiers in immunology2021

Noninvasive Immuno-PET Imaging of CD8

Paul W Rothlauf, Zeyang Li, Novalia Pishesha, Yushu Joy Xie, Andrew W Woodham, Djenet Bousbaine, Stephen C Kolifrath, Vincent L Verschoor, Hidde L Ploegh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Specific imaging of CD8 + T-Cell dynamics with a nanobody radiotracer against human CD8β.European journal of nuclear medicine and molecular imaging · 2024
    Article
  3. Review
  4. Review
  5. Imaging-Selected Host Responses in the Context of Infections.The Journal of infectious diseases · 2023
    Article
  6. Review
  7. Single-Domain Antibody Theranostics on the Horizon.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Paul W RothlaufProgram in Virology, Harvard Medical School, Boston, MA, United States.
Zeyang LiProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Novalia PisheshaProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Yushu Joy XieProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Andrew W WoodhamProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Djenet BousbaineProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Stephen C KolifrathProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Vincent L VerschoorProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Hidde L PloeghProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, United States.
Boston Children's Hospital · USHarvard University · USLeiden University · NLWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immuno-positron emission tomography (immuno-PET) is a noninvasive imaging method that enables tracking of immune cells in living animals. We used a nanobody that recognizes mouse CD8α and labeled it with

Indexed as

Amino Acid SequenceAnimalsBiomarkersCD8-Positive T-LymphocytesCell TrackingDisease Models, AnimalImmunophenotypingInfluenza A virusMiceModels, MolecularMolecular ImagingMolecular ProbesOrthomyxoviridae InfectionsPeptidesPositron-Emission TomographyBiomarkersMolecular ProbesPeptidesCD8imagingimmuno-PETinfluenza A virusT cells

Identifiers

PMID34804069
PMCPMC8595544
OpenAlexW3208623817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.