Evidence map›Paper›PMID 34804037›Full record

ArticleFrontiers in immunology2021

Innate Memory Reprogramming by Gold Nanoparticles Depends on the Microbial Agents That Induce Memory.

Benjamin J Swartzwelter, Sara Michelini, Tobias Frauenlob, Francesco Barbero, Alessandro Verde, Anna Chiara De Luca, Victor Puntes, Albert Duschl, Jutta Horejs-Hoeck, Paola Italiani and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Benjamin J SwartzwelterInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Sara MicheliniDepartment Biosciences, Paris Lodron University of Salzburg (PLUS), Salzburg, Austria.
Tobias FrauenlobDepartment Biosciences, Paris Lodron University of Salzburg (PLUS), Salzburg, Austria.
Francesco BarberoInstitut Català de Nanociència i Nanotecnologia (ICN2), Consejo Superior de Investigaciones Científicas (CSIC) and The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Alessandro VerdeInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Anna Chiara De LucaInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Victor PuntesInstitut Català de Nanociència i Nanotecnologia (ICN2), Consejo Superior de Investigaciones Científicas (CSIC) and The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Albert DuschlDepartment Biosciences, Paris Lodron University of Salzburg (PLUS), Salzburg, Austria.
Jutta Horejs-HoeckDepartment Biosciences, Paris Lodron University of Salzburg (PLUS), Salzburg, Austria.
Paola ItalianiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
Diana BoraschiInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Napoli, Italy.
National Research Council · ITUniversity of Salzburg · ATChinese Academy of Sciences · CNConsejo Superior de Investigaciones Científicas · ESInstitut Català de Nanociència i Nanotecnologia · ES

Funding

Austrian Science Fund FWF P 29941
6 · The paper itself

Abstract

Innate immune memory, the ability of innate cells to react in a more protective way to secondary challenges, is induced by exposure to infectious and other exogeous and endogenous agents. Engineered nanoparticles are particulate exogenous agents that, as such, could trigger an inflammatory reaction in monocytes and macrophages and could therefore be also able to induce innate memory. Here, we have evaluated the capacity of engineered gold nanoparticles (AuNPs) to induce a memory response or to modulate the memory responses induced by microbial agents. Microbial agents used were in soluble

Indexed as

Candida albicansHelicobacter pyloriStaphylococcus aureusbeta-GlucansCells, CulturedCytokinesGoldHumansImmunity, InnateImmunologic MemoryMetal NanoparticlesMonocytesbeta-GlucansCytokinesGoldinnate immunityinnate memorymicrobial agentsmonocytesnanoparticles

Identifiers

PMID34804037
PMCPMC8600232
OpenAlexW3210884999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.