Evidence map›Paper›PMID 34804004›Full record

ArticleFrontiers in immunology2021

Intestinal CD11b

Ying Fu, Zhiming Wang, Baichao Yu, Yuli Lin, Enyu Huang, Ronghua Liu, Chujun Zhao, Mingfang Lu, Wei Xu, Hongchun Liu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 24 citations in OpenAlex.

  1. Gut microbes · 2026
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  6. M2 macrophages promote IL-10Immunotherapy advances · 2025
    Article
  7. Review
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  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Ying FuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhiming WangDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Baichao YuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Yuli LinDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Enyu HuangDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Ronghua LiuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Chujun ZhaoDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Mingfang LuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wei XuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Hongchun LiuDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yongzhong LiuState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Luman WangDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Yiwei ChuDepartment of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Fudan University · CNColumbia University · USShanghai Cancer Institute · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal mucosal immune environment requires multiple immune cells to maintain homeostasis. Although intestinal B cells are among the most important immune cells, little is known about the mechanism that they employ to regulate immune homeostasis. In this study, we found that CD11b

Indexed as

Adoptive TransferAnimalsB-LymphocytesCD11b AntigenColitisColitis, UlcerativeDextran SulfateDisease Models, AnimalHumansImmunoglobulin A, SecretoryImmunoglobulin Class SwitchingIntestinal MucosaMiceMice, Inbred C57BLMice, KnockoutPeyer's PatchesCD11b AntigenDextran SulfateImmunoglobulin A, SecretorySmad2 ProteinCD11b+ B cellsDSS-induced colitisIgASmadTGF-β

Identifiers

PMID34804004
PMCPMC8595478
OpenAlexW3210055504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.