Evidence map›Paper›PMID 34803895›Full record

ArticleFrontiers in neurology2021

Genistein, a Natural Isoflavone, Alleviates Seizure-Induced Respiratory Arrest in DBA/1 Mice.

Jialing Guo, Daniel Min, Hua-Jun Feng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Genistein and Vanadate Differentially Modulate Cortical GABAInternational journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jialing GuoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Daniel MinDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States.
Hua-Jun FengDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States.
Massachusetts General Hospital · USCentral South University · CN

Funding

Prevention of Seizure-Induced Sudden Death by Stimulating Serotonergic SignalingR01NS112319 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI FENG, HUAJUN · 2020 to 2024
$1.9M
NINDS NIH HHS R01 NS112319
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dietary supplementnorepinephrineserotoninS-IRASUDEPtherapeutics

Identifiers

PMID34803895
PMCPMC8599950
OpenAlexW3212266160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.