Evidence map›Paper›PMID 34803745›Full record

ArticleFrontiers in physiology2021

Doxycycline Changes the Transcriptome Profile of mIMCD3 Renal Epithelial Cells.

Hyun Jun Jung, Richard Coleman, Owen M Woodward, Paul A Welling

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hyun Jun JungDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Richard ColemanDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Owen M WoodwardDepartment of Physiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Paul A WellingDivision of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins Medicine · USUniversity of Maryland, Baltimore · US

Funding

WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1M
Research BaseP30DK090868 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI WATNICK, TERRY J · 2010 to 2019
$11.1M
Molecular of ROMK Channel FunctionR01DK054231 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI Paul A Welling · 1998 to 2026
$7.7M
OXGR1 in Renal Intercalated Cells, Salt Transport and Diuretic EfficacyR01DK110375 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, SUSAN MARIE WALL · 2017 to 2026
$6.7M
NIDDK NIH HHS P30 DK090868NIDDK NIH HHS R01 DK054231NIDDK NIH HHS R01 DK093501NIDDK NIH HHS R01 DK110375
6 · The paper itself

Abstract

Tetracycline-inducible gene expression systems have been used successfully to study gene function

Indexed as

cell proliferationdoxycyclinemIMCD3RNA-seqtranscriptional response

Identifiers

PMID34803745
PMCPMC8602682
OpenAlexW3214348689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.