Evidence map›Paper›PMID 34803737›Full record

ReviewFrontiers in physiology2021

Generation and Export of Red Blood Cell ATP in Health and Disease.

Timothy J McMahon, Cole C Darrow, Brooke A Hoehn, Hongmei Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 48 citations in OpenAlex.

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  16. Influence ofBiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Timothy J McMahonDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Durham VA and Duke University Medical Centers, Durham, NC, United States.
Cole C DarrowDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Durham VA and Duke University Medical Centers, Durham, NC, United States.
Brooke A HoehnDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Durham VA and Duke University Medical Centers, Durham, NC, United States.
Hongmei ZhuDepartment of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Durham VA and Duke University Medical Centers, Durham, NC, United States.
Duke Medical Center · USDuke University Hospital · US

Funding

An Improved Red Blood Cell Storage Product and Extended Shelf Life using a Normoglycemic Additive SolutionR01HL156440 · NHLBI · MICHIGAN STATE UNIVERSITY · PI MCMAHON, TIMOTHY J, SPENCE, DANA M · 2021 to 2024
$2.0M
BLRD VA I01 BX003478NHLBI NIH HHS R01 HL156440
6 · The paper itself

Abstract

Metabolic homeostasis in animals depends critically on evolved mechanisms by which red blood cell (RBC) hemoglobin (Hb) senses oxygen (O

Indexed as

blood flowendothelial cellshypoxiasepsistransfusion

Identifiers

PMID34803737
PMCPMC8602689
OpenAlexW3212356617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.