Evidence map›Paper›PMID 34803668›Full record

ArticleFrontiers in pharmacology2021

Higher Risk of Cardiovascular Diseases in Rheumatoid Arthritis Patients Without Methotrexate Treatment.

Karel Hloch, Martin Doseděl, Jurjen Duintjer Tebbens, Lenka Žaloudková, Helena Medková, Jiří Vlček, Tomáš Soukup, Petr Pávek

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. [Pathogenesis and potential diagnostic biomarkers of atrial fibrillation in Chinese population: a study based on bioinfor-matics].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karel HlochDepartment of Social & Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czechia.
Martin DosedělDepartment of Social & Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czechia.
Jurjen Duintjer TebbensDepartment of Biophysics & Physical Chemistry, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czechia.
Lenka ŽaloudkováInstitute of Clinical Biochemistry and Diagnostics, University Hospital Hradec Kralove, Hradec Kralove, Czechia.
Helena Medková2nd Department of Internal Medicine - Gastroenterology, Division Rheumatology, Faculty of Medicine & University Hospital in Hradec Kralove, Charles University, Hradec Kralove, Czechia.
Jiří VlčekDepartment of Social & Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czechia.
Tomáš Soukup2nd Department of Internal Medicine - Gastroenterology, Division Rheumatology, Faculty of Medicine & University Hospital in Hradec Kralove, Charles University, Hradec Kralove, Czechia.
Petr PávekDepartment of Pharmacology & Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czechia.
Charles University · CZUniversity Hospital Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) lead to higher morbidity and mortality in rheumatoid arthritis; thus, we aimed to determine whether patients who had discontinued methotrexate treatment before the study enrollment (group MTX 0) were at a higher risk of CVD than patients treated with methotrexate at the time of the data collection (group MTX 1). A retrospective, prospective, observational, cross-sectional study was conducted. A total of 125 patients were enrolled in the study. Patients from the MTX 0 group (

Indexed as

cardiovascular diseasescardiovascular risk factorsmethotrexatemethotrexate discontinuationrheumatoid arthritis

Identifiers

PMID34803668
PMCPMC8602828
OpenAlexW3211530385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.