Evidence map›Paper›PMID 34803652›Full record

ArticleFrontiers in aging neuroscience2021

Gender Difference in Associations Between Telomere Length and Risk Factors in Patients With Stroke.

Yuqing Wang, Fengjuan Jiao, Huancheng Zheng, Qingsheng Kong, Ran Li, Xiaojie Zhang, Li Yan, Yanlei Hao, Yili Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. [Environmental relative humidity, frailty, and risk of incident stroke among middle-aged and older adults in China: A prospective cohort study].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yuqing WangCheeloo College of Medicine, Shandong University, Jinan, China.
Fengjuan JiaoShandong Collaborative Innovation Center for Diagnosis, Treatment and Behavioral Interventions of Mental Disorders, Institute of Mental Health, Jining Medical University, Jining, China.
Huancheng ZhengCheeloo College of Medicine, Shandong University, Jinan, China.
Qingsheng KongCollaborative Innovation Center for Birth Defect Research and Transformation of Shandong Province, Jining Medical University, Jining, China.
Ran LiCheeloo College of Medicine, Shandong University, Jinan, China.
Xiaojie ZhangDepartment of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, China.
Li YanDepartment of Neurology, China-Japan Friendship Hospital, Beijing, China.
Yanlei HaoDepartment of Neurology, Affiliated Hospital of Jining Medical University, Jining, China.
Yili WuKey Laboratory of Alzheimer's Disease of Zhejiang Province, Institute of Aging, School of Mental Health, Wenzhou Medical University, Wenzhou, China.
Jining Medical University · CNShandong University · CNAffiliated Hospital of Jining Medical University · CNChina-Japan Friendship Hospital · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple risk factors of stroke are associated with telomere length shortening. Although leukocyte telomere length (LTL) is shorter in patients with stroke, the heterogeneity is high. Risk factors may be differentially associated with LTL in male and female patients contributing to the heterogeneity. However, the gender difference in associations between LTL and risk factors in stroke patients has not been investigated. In this study, we investigated the gender difference in associations between LTL and risk factors in 312 stroke patients. Real-time quantitative PCR was used to determine relative LTL, and multiple linear regression analysis was applied for association analyses. We found that LTL was negatively associated with triglyceride (TG) in all patients [β(95% CI) = -0.69 (-1.26, -0.11),

Indexed as

gendergender differencerisk factorsstroketelomere length

Identifiers

PMID34803652
PMCPMC8600313
OpenAlexW3210489773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.