Evidence map›Paper›PMID 34803592›Full record

ArticleFrontiers in neuroscience2021

Improving Deep Brain Stimulation Electrode Performance

Tomoko Hyakumura, Ulises Aregueta-Robles, Wenlu Duan, Joel Villalobos, Wendy K Adams, Laura Poole-Warren, James B Fallon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tomoko HyakumuraThe Bionics Institute of Australia, East Melbourne, VIC, Australia.
Ulises Aregueta-RoblesGraduate School of Biomedical Engineering, The University of New South Wales, Sydney, NSW, Australia.
Wenlu DuanGraduate School of Biomedical Engineering, The University of New South Wales, Sydney, NSW, Australia.
Joel VillalobosThe Bionics Institute of Australia, East Melbourne, VIC, Australia.
Wendy K AdamsThe Bionics Institute of Australia, East Melbourne, VIC, Australia.
Laura Poole-WarrenGraduate School of Biomedical Engineering, The University of New South Wales, Sydney, NSW, Australia.
James B FallonThe Bionics Institute of Australia, East Melbourne, VIC, Australia.
UNSW Sydney · AUBionics Institute · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson's disease and more recently, in psychiatric conditions like obsessive compulsive disorder. Electrode-tissue interfaces that support safe and effective targeting of specific brain regions are critical to success of these devices. Development of directional electrodes that activate smaller volumes of brain tissue requires electrodes to operate safely with higher charge densities. Coatings such as conductive hydrogels (CHs) provide lower impedances and higher charge injection limits (CILs) than standard platinum electrodes and support safer application of smaller electrode sizes. The aim of this study was to examine the chronic

Indexed as

conductive hydrogeldeep brain stimulationelectrical propertieselectrode coatingneural stimulationtissue response

Identifiers

PMID34803592
PMCPMC8602793
OpenAlexW3214417674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.