Evidence map›Paper›PMID 34803544›Full record

ArticleContrast media & molecular imaging2021

Comparison of Rhenium and Iodine as Contrast Agents in X-Ray Imaging.

José Carlos De La Vega, Pedro Luis Esquinas, Jovan Kaur Gill, Selin Jessa, Bradford Gill, Yogesh Thakur, Katayoun Saatchi, Urs O Häfeli

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Protein-functionalized and intrinsically radiolabeled [European journal of nuclear medicine and molecular imaging · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

José Carlos De La VegaFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-4272-2389
Pedro Luis EsquinasMedical Imaging Research Group, Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-8577-6083
Jovan Kaur GillFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Selin JessaFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Bradford GillMedical Physics Department, BC Cancer, Vancouver, British Columbia, Canada.
Yogesh ThakurDepartment of Radiology, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-5846-0478
Katayoun SaatchiFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-5372-6791
Urs O HäfeliFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-0671-4509
University of British Columbia · CASpinal Cord Injury BC · CAVancouver Coastal Health · CA

Funding

CIHR
6 · The paper itself

Abstract

Purpose: The majority of X-ray contrast agents (XCA) are made with iodine, but iodine-based XCA (I-XCA) exhibit low contrast in high kVp X-rays due to iodine's low atomic number ( Results: I-XCA have a greater contrast-to-noise ratio (CNR) at 50 and 80 kVp, but Re-XCA have a greater CNR at >120 kVp. The difference in CNR is increased as the thickness of the copper filters is increased. For instance, the percent CNR improvement of rhenium over iodine is 14.2% with a 0.6 mm thick copper filter, but it is 59.1% with a 1.6 mm thick copper filter, as shown at 120 kVp by Conclusions: Using Monte Carlo simulations, we showed that it is possible to reduce the absorbed dose of high kVp X-rays while allowing the acquisition of high-quality images. Furthermore, radiopaque catheters have the potential of enhancing the contrast during catheterizations and helping physicians to place catheters inside patients more rapidly and precisely.

Indexed as

IodineRheniumContrast MediaHumansPhantoms, ImagingX-Ray MicrotomographyX-RaysContrast MediaIodineRhenium

Identifiers

PMID34803544
PMCPMC8575601
OpenAlexW3209109030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.