Evidence map›Paper›PMID 34803415›Full record

ReviewNature and science of sleep2021

Sleep-Related Hypermotor Epilepsy: Etiology, Electro-Clinical Features, and Therapeutic Strategies.

Huijuan Wan, Xing Wang, Yiyi Chen, Bin Jiang, Yangmei Chen, Wenhan Hu, Kai Zhang, Xiaoqiu Shao

Open access · goldAbstract readReview
In one paragraph

Review in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. NovelFrontiers in neuroscience · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Huijuan Wan *Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0001-6500-8642
Xing Wang *Department of Neurology, Chongqing University Central Hospital, Chongqing Emergency Medical Centre, Chongqing, People's Republic of China.
Yiyi ChenDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Bin JiangDepartment of Neurology, First Affiliated Hospital, Xiamen University, Xiamen, People's Republic of China.
Yangmei ChenDepartment of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Wenhan HuBeijing Neurosurgical Institute, Capital Medical University, Beijing, People's Republic of China.
Kai ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Xiaoqiu ShaoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CNChongqing University · CNFirst Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep-related hypermotor epilepsy (SHE) is a group of clinical syndromes with heterogeneous etiologies. SHE is difficult to diagnose and treat in the early stages due to its diverse clinical manifestations and difficulties in differentiating from non-epileptic events, which seriously affect patients' quality of life and social behavior. The overall prognosis for SHE is unsatisfactory, but different etiologies affect patients' prognoses. Surgical treatment is an effective method for carefully selected patients with refractory SHE; nevertheless, preoperative assessment remains challenging because of the low sensitivity of noninvasive scalp electroencephalogram and imaging to detect abnormalities. However, through a careful analysis of semiology, the clinician can deduce the potential epileptogenic zone. This paper summarizes the research status of the background, etiology, electro-clinical features, diagnostic criteria, prognosis, and treatment of SHE to provide a more in-depth understanding of its pathophysiological mechanism, improve the accuracy in the diagnosis of this group of syndromes, and further explore more targeted therapy plans.

Indexed as

electroencephalogramepileptogenic zonehypermotorseizure onset zonesemiologySOZ

Identifiers

PMID34803415
PMCPMC8598206
OpenAlexW3214122963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.