ReviewVascular health and risk management2021
Heart Rate Variability and Cardiovascular Fitness: What We Know so Far.
Review in Vascular health and risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physical Exercise Effects on Cardiovascular Autonomic Modulation in Postmenopausal Women-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Combined effect of physical exercise and hormone replacement therapy on cardiovascular and metabolic health in postmenopausal women: A systematic review and meta-analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023Pooled it
- Short-term effects of weight-loading on heart rate variability in obese adults.Physiological reports · 2026Trial
- Analysis of clinical and heart rate variability parameters associated with single-vessel and multivessel coronary artery disease: A retrospective study.Pakistan journal of medical sciences · 2026Article
- Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026Review
- The Relationship Between Heart Rate Variability and Interoception in Anorexia Nervosa Spectrum Disorders.The International journal of eating disorders · 2026Article
- Associations Between High-Density Lipoprotein Subfraction Profiles and Heart Rate Response Following Submaximal Exercise.Biology · 2026Article
- Perceptions of the Likelihood and Importance of Physical Activity Outcomes at 14 Years Affects Physical Fitness at 17 Years.Child: care, health and development · 2026Article
- Predictive value of intraoperative hemodynamics and heart rate variability for postoperative emergence quality in children undergoing transcatheter VSD closure.Journal of cardiothoracic surgery · 2026Article
- Autonomic Dysfunction and Functional Impairment in Candidates for Metabolic Bariatric Surgery: A High Vulnerability Profile.Obesity surgery · 2026Article
- Metabolic signatures of the integrated profile of cardiovascular autonomic modulation and cardiorespiratory fitness in apparently healthy individuals.Physiological reports · 2026Article
- Cardiac Autonomic Dysfunction and Increased Oxidative Stress in Conventional Cigarettes and E-Cigarettes: Heart Rate Variability as a Cardiovascular Predictor.Antioxidants (Basel, Switzerland) · 2025Review
- Impact of Obstructive Sleep Apnea-Hypopnea Syndrome Severity on Heart Rate Variability and QTc Interval in Hypertensive Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Within-person associations of daily activity to sleep actigraphy following trauma: Explicating a novel index of risk for major depressive disorder and posttraumatic stress disorder.Journal of psychopathology and clinical science · 2025Article
- Lifestyle Interventions to Tackle Cardiovascular Risk in Thyroid Hormone Signaling Disorders.Nutrients · 2025Review
- Identification of Athleticism and Sports Profiles Throughout Machine Learning Applied to Heart Rate Variability.Sports (Basel, Switzerland) · 2025Article
- A short bout of low to moderate aerobic exercise influences cognitive performance in healthy adults based on task type, timing, and individual factors.Frontiers in sports and active living · 2025Article
- Heart rate variability, a potential assessment tool for identifying anxiety, depression, and sleep disorders in elderly individuals.Frontiers in psychiatry · 2025Article
- Article
- Heart rate variability and its modulation by nutrients: a narrative review on implications for cardiovascular aging.Frontiers in neuroscience · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluctuation analysis in intervals between heartbeats provides important indices related to autonomic modulation of heart rate variability (HRV). These indices are considered predictors of morbidity and mortality as they are frequently altered in patients with chronic degenerative diseases, especially in those with cardiovascular and metabolic diseases. Similarly, a reduction in HRV is common with aging. In all cases, cardiovascular fitness is often reduced to below the predicted values. In turn, increases in cardiovascular fitness through regular physical exercise, especially aerobic exercise, represent an important therapeutic tool capable of promoting positive adjustments in cardiac autonomic modulation. These adjustments are characterized by reduced sympathetic modulatory influence and/or increased vagal modulatory influence on the heart, increasing the HRV. Therefore, several methodological tools have been used to assess the degree of impairment of autonomic modulation and the therapeutic effects of physical exercise. In contrast, establishment of strict protocols in experimental design is a main challenge in establishing HRV analysis as a robust parameter for evaluating cardiovascular homeostasis. Thus, this review aimed to contribute to the understanding of autonomic modulation of HRV and its relationship with cardiovascular fitness, highlighting the advances made thus far, the applicability of analysis tools, and the confounding factors observed frequently.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.