ArticleAnnals of emergency medicine2022
Naloxone and Buprenorphine Prescribing Following US Emergency Department Visits for Suspected Opioid Overdose: August 2019 to April 2021.
Article in Annals of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Behavioral and Psychosocial Predictors of Treatment Response in Emergency Psychiatric Admissions for Substance Use Disorders in a Socioeconomically Vulnerable Region of Southeastern Romania: A Five-Year Retrospective Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- The Importance of Addiction Medicine Education for Emergency Medicine Residents and Opportunities to Increase Uptake of Evidence-Based Interventions for Substance Use Disorder.Annals of emergency medicine · 2026Article
- Emergency Departments Need to Train and Hire More Sub-Specialists in Addiction Medicine.AEM education and training · 2026Article
- Inpatient utilization among Medicaid members with substance use disorder in Oregon.Substance abuse treatment, prevention, and policy · 2026Article
- Review
- Timely Receipt of New Medication Treatment After Acute Care Encounters for Opioid Overdose in the U.S. Medicaid Population.Journal of general internal medicine · 2026Article
- Naloxone Disparities in Adolescents: Access Laws Are Not Enough.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients.JAMA network open · 2025Article
- Medicaid Patients With ED Visits For Overdose: Disparities In Initiation Of Medications For Opioid Use Disorder.Health affairs (Project Hope) · 2025Article
- Clinical Decision Support to Increase Emergency Department Naloxone Coprescribing: Implementation Report.JMIR medical informatics · 2024Article
- Facilitators of and barriers to buprenorphine initiation in the emergency department: a scoping review.Lancet regional health. Americas · 2024Article
- A Statewide Consultation Helpline for Rapid Linkage to Services for Youths With Opioid Use Disorder and Other Substance Use.Psychiatric services (Washington, D.C.) · 2024Article
- Age and racial and ethnic disparities in filled buprenorphine prescriptions post-emergency department visit in Nevada.Journal of the American College of Emergency Physicians open · 2024Article
- Article
- Drug-related physician continuing medical education requirements, 2010-2020.Journal of substance use and addiction treatment · 2024Article
- Naloxone distribution programs in the emergency department: A scoping review of the literature.Journal of the American College of Emergency Physicians open · 2024Article
- Is a randomised controlled trial of take home naloxone distributed in emergency settings likely to be feasible and acceptable? Findings from a UK qualitative study exploring perspectives of people who use opioids and emergency services staff.BMC emergency medicine · 2024Article
- Barriers and Facilitators to Harm Reduction for Opioid Use Disorder: A Qualitative Study of People With Lived Experience.Annals of emergency medicine · 2024Article
- Pregnancy and Postpartum Drug Overdose Deaths in the US Before and During the COVID-19 Pandemic.JAMA psychiatry · 2024Article
- Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
STUDY
objectiveNonfatal emergency department (ED) visits for opioid overdose are important opportunities to prescribe naloxone and buprenorphine, both of which can prevent future overdose-related mortality. We assessed the rate of this prescribing using national data from August 2019 to April 2021, a period during which US opioid overdose deaths reached record levels.
methodsWe conducted a retrospective cohort analysis using Symphony Health's Integrated Dataverse, which includes data from 5,800 hospitals and 70,000 pharmacies. Of ED visits for opioid overdose between August 4, 2019, and April 3, 2021, we calculated the proportion with at least 1 naloxone prescription within 30 days and repeated this analysis for buprenorphine. To contextualize the naloxone prescribing rate, we calculated the proportion of ED visits for anaphylaxis with at least 1 prescription for epinephrine-another life-saving rescue medication-within 30 days.
resultsAnalyses included 148,966 ED visits for opioid overdose. Mean weekly visits increased 23.6% during the period between April 26, 2020 and October 3, 2020 compared with the period between August 4, 2019 to April 25, 2020. Visits declined to prepandemic levels between October 4, 2020 and March 13, 2021, after which visits began to rise. Naloxone and buprenorphine were prescribed within 30 days at 7.4% and 8.5% of the 148,966 visits, respectively. The naloxone prescribing rate (7.4%) was substantially lower than the epinephrine prescribing rate (48.9%) after ED visits for anaphylaxis.
conclusionBetween August 4, 2019, and April 3, 2021, naloxone and buprenorphine were only prescribed after 1 in 13 and 1 in 12 ED visits for opioid overdose, respectively. Findings suggest that clinicians are missing critical opportunities to prevent opioid overdose-related mortality.
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