Trial reportBMC pregnancy and childbirth2021
Randomized trial examining the effect of exercise and wellness interventions on preventing postpartum depression and perceived stress.
Trial report in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01883479 (Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression.), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression.
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Physical activity modalities and dosing for postpartum depression, anxiety and quality of life: a network meta-analysis and dose response of randomized trials.BMC public health · 2026Pooled it
- Pooled it
- Comparative effectiveness and certainty of exercise-based interventions for postpartum depressive symptoms: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2026Pooled it
- Optimal dose of aerobic exercise for improving postpartum depression, anxiety, and quality of life: a meta-analysis of randomized controlled trials and dose-response analysis.Frontiers in public health · 2026Pooled it
- Interventions to Prevent Relapse or Recurrence of Preconception Anxiety and/or Depression in Perinatal Women: A Systematic Review.Maternal and child health journal · 2025Pooled it
- Comparative Effectiveness of Multiple Exercise Interventions in the Treatment of Mental Health Disorders: A Systematic Review and Network Meta-Analysis.Sports medicine - open · 2022Pooled it
- Integrating mental health into obstetric practice: a review of collaborative care models for perinatal anxiety.Journal of perinatal medicine · 2026Review
- Non-Pharmacological Strategies for Postpartum Depression: A Network Meta-Analysis of Randomized Controlled Trials.Iranian journal of psychiatry · 2026Review
- Summary of current evidence for digital health interventions in the screening and management of postpartum depression.Frontiers in psychiatry · 2026Article
- Effects of lifestyle intervention by a nurse-led app on the prevention of symptoms in postpartum women: a randomized controlled trial.BMC nursing · 2025Article
- Article
- From Pregnancy to Breastfeeding: The Role of Maternal Exercise in Preventing Childhood Obesity.Nutrients · 2025Review
- Non-pharmacological Radical Methods for Treating Postpartum Depression Around the Globe: A Narrative Review.Cureus · 2024Review
- Content, Behaviour Change Techniques, and Quality of Postpartum Depression Apps to Be Recommended by Midwives: Systematic Search and Evaluation.Nursing reports (Pavia, Italy) · 2024Article
- Wheel Running During Pregnancy Alleviates Anxiety-and Depression-Like Behaviors During the Postpartum Period in Mice: The Roles of NLRP3 Neuroinflammasome Activation, Prolactin, and the Prolactin Receptor in the Hippocampus.Neurochemical research · 2024Article
- Postpartum symptoms of anxiety, depression and stress: differential relationships to women's cortisol profiles.Archives of women's mental health · 2024Article
- Assessment of Postpartum Stress Using the Maternal Postpartum Stress Scale (MPSS) in Spanish Women.Healthcare (Basel, Switzerland) · 2024Article
- Review
- 'A tool we need': Midwives' descriptions and recommendations of an ideal obstetric triage tool.Health SA = SA Gesondheid · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundApproximately 13-19% of postpartum women experience postpartum depression and a majority report at least some stress during the postpartum phase. Traditional interventions such as psychotherapy and antidepressant medications are often not feasible or desirable. The purpose of this study was to examine two low cost, brief, accessible interventions designed to prevent postpartum depression and perceived stress among women at high risk.
methodsParticipants (n = 450) who were on average four weeks postpartum, had a history of depression before pregnancy, and exercised less than 60 min per week were randomly assigned to one of the following three conditions: (1) 6-month telephone-based exercise intervention; (2) 6-month telephone-based wellness/support intervention (e.g., healthy eating, sleep, and perceived stress); or (3) usual care.
resultsOverall, 2.4% of participants met criteria for depression at 6 months and 3.6% at 9 months with no differences between groups. At 6 months following randomization, median symptoms of depression were significantly lower among wellness participants compared to usual care participants (b = - 1.00, SE = 0.46, p = .03). Perceived stress at 6 months post-randomization was significantly lower among exercise vs. usual care participants (b = - 2.00, SE = .98, p = .04) and exercise vs. wellness participants (b = - 2.20, SE = 1.11, p = .04).
conclusionsThe wellness intervention was efficacious for preventing symptoms of depression; however, postpartum depression that met the diagnostic criteria was surprisingly low in all conditions among this at risk sample of postpartum women. Exercise interventions may have a protective effect on perceived stress among women at risk for postpartum depression. Practitioners should consider integrating exercise and wellness interventions into postpartum care.
trial registrationClinical Trials Number: NCT01883479 (06/21/2013).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.