Evidence map›Paper›PMID 34802292›Full record

ArticleNanomedicine (London, England)2021

Nasal delivery of nanotherapeutics for CNS diseases: challenges and opportunities.

Anisha A D'Souza, Shallu Kutlehria, Di Huang, Benjamin S Bleier, Mansoor M Amiji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomedicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anisha A D'SouzaMassachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-2457-671X
Shallu KutlehriaDepartment of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-6722-3709
Di HuangMassachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-6809-6470
Benjamin S BleierMassachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-0783-8861
Mansoor M AmijiDepartment of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0001-6170-881X

Funding

Direct CNS Delivery System for BDNF AntagoNATs using Heterotopic Mucosal Grafting for the Treatment of Parkinson's DiseaseR01NS108968 · NINDS · MASSACHUSETTS EYE AND EAR INFIRMARY · PI BLEIER, BENJAMIN · 2019 to 2023
$2.5M
NINDS NIH HHS R01 NS108968
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood-Brain BarrierCentral Nervous System DiseasesAdministration, IntranasalBrainDrug Delivery SystemsHumansblood–brain barrierCNS diseasesMINDmucosal graftingnose-to-brain delivery

Identifiers

PMID34802292
PMCPMC8739396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.