Evidence map›Paper›PMID 34802257›Full record

ArticleEpigenomics2021

Methylome of skeletal muscle tissue in patients with hypertension and diabetes undergoing cardiopulmonary bypass.

Ghazal Aghagoli, Andrew Del Re, Naohiro Yano, Zhiqi Zhang, Ahmad Aboul Gheit, Ronald K Phillips, Frank W Sellke, Alexey V Fedulov

Open access · greenAbstract readControlled Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ghazal AghagoliAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Andrew Del ReAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Naohiro YanoAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Zhiqi ZhangAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Ahmad Aboul GheitAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Ronald K PhillipsAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Frank W SellkeAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.
Alexey V FedulovAlpert Medical School of Brown University, Department of Surgery, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA.ORCID 0000-0002-8226-2236
Brown University · US

Funding

Effect of Cardioplegia and Cardiopulmonary Bypass on Coronary Microvascular ReactivityR01HL046716 · NHLBI · RHODE ISLAND HOSPITAL · PI SELLKE, FRANK W · 1997 to 2023
$8.5M
Vascular Dysfunction in Myocardial Ischemia and Metabolic SyndromeR01HL128831 · NHLBI · RHODE ISLAND HOSPITAL · PI SELLKE, FRANK W, USHEVA-SIMIDJIYSKA, ANNY · 2016 to 2025
$5.7M
Microbiome in Asthma Induced by Environmental Particle ExposureR01ES030227 · NIEHS · J. CRAIG VENTER INSTITUTE, INC. · PI FEDULOV, ALEXEY V, GONZALEZ-JUARBE, NORBERTO · 2019 to 2023
$3.4M
NHLBI NIH HHS R01 HL046716NHLBI NIH HHS R01 HL128831NIEHS NIH HHS R01 ES030227
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiopulmonary BypassDiabetes MellitusDNA MethylationHypertensionAgedCytokinesFemaleHippo Signaling PathwayHumansMaleMiddle AgedMuscle, SkeletalNF-kappa BVascular Endothelial Growth Factor AWnt Signaling PathwayCytokinesNF-kappa BVascular Endothelial Growth Factor AVEGFA protein, humancardiac surgerycardiopulmonary bypass (CPB)diabetesDNA methylationepigenomicshypertensionskeletal muscle

Identifiers

PMID34802257
PMCPMC8619827
OpenAlexW3215278453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.