Evidence map›Paper›PMID 34802072›Full record

ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2022

Mechanisms of COVID-19-induced kidney injury and current pharmacotherapies.

Wissam H Faour, Ali Choaib, Elio Issa, Francesca El Choueiry, Khodor Shbaklo, Maryline Alhajj, Ramy Touma Sawaya, Zeina Harhous, Eman Alefishat, Moni Nader

Open access · hybridAbstract readReview
In one paragraph

Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Cytokine storm in acute respiratory distress syndrome.Journal of intensive medicine · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. COVID-19 associated acute kidney injury.Infectious diseases & immunity · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Wissam H Faour *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon. wissam.faour@lau.edu.lb.
Ali Choaib *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Elio Issa *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Francesca El Choueiry *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Khodor Shbaklo *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Maryline Alhajj *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Ramy Touma Sawaya *Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Zeina HarhousGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Eman AlefishatDepartment of Pharmacology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, P.O. Box 127788, Abu Dhabi, United Arab Emirates.
Moni NaderDepartment of Physiology and Immunology, College of Medicine and Health Sciences, Khalifa University of Science and Technology, P.O. Box 127788, Abu Dhabi, United Arab Emirates. moni.nader@ku.ac.ae.ORCID http://orcid.org/0000-0003-2138-5213
Lebanese American University · LBKhalifa University of Science and Technology · AEUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic created a worldwide debilitating health crisis with the entire humanity suffering from the deleterious effects associated with the high infectivity and mortality rates. While significant evidence is currently available online and targets various aspects of the disease, both inflammatory and noninflammatory kidney manifestations secondary to COVID-19 infection are still largely underrepresented. In this review, we summarized current knowledge about COVID-19-related kidney manifestations, their pathologic mechanisms as well as various pharmacotherapies used to treat patients with COVID-19. We also shed light on the effect of these medications on kidney functions that can further enhance renal damage secondary to the illness.

Indexed as

COVID-19 Drug TreatmentAcute Kidney InjuryAldosteroneAngiotensinsAntibodies, Monoclonal, HumanizedAutopsyBiopsyCOVID-19COVID-19 VaccinesDexamethasoneEnoxaparinHeparinHeparin, Low-Molecular-WeightHumansInflammationInterleukin 1 Receptor Antagonist ProteinAldosteroneAngiotensinsAntibodies, Monoclonal, HumanizedCOVID-19 VaccinesDexamethasoneEnoxaparinHeparinHeparin, Low-Molecular-WeightInterleukin 1 Receptor Antagonist ProteinLopinavirRitonavirtocilizumabAngiotensinCOVID-19InflammationKidneyRenal pathology

Identifiers

PMID34802072
PMCPMC8606168
OpenAlexW3215772098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.