ArticleInternational journal of obesity (2005)2022
Metabolic health, menopause, and physical activity-a 4-year follow-up study.
Article in International journal of obesity (2005), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Religious fasting and its impacts on individual, public, and planetary health: Fasting as a "religious health asset" for a healthier, more equitable, and sustainable society.Frontiers in nutrition · 2022Pooled it
- Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats.Experimental physiology · 2026Article
- Association between physical activity and mortality in postmenopausal women: evidence from NHANES 2007-2018.BMC women's health · 2026Article
- Adipose-muscle crosstalk during the menopausal transition: mechanistic links to sarcopenic obesity in midlife women.Frontiers in endocrinology · 2026Review
- Aerobic training effects on knee joint laxity and estrogen levels in post-menopausal women with type 2 diabetes: a randomized controlled trial.Journal of diabetes and metabolic disorders · 2025Article
- Sex- and endurance training-mediated cardiovascular protection through lipids during exercise.Trends in endocrinology and metabolism: TEM · 2025Review
- Vitamin D sufficiency and its relationship with muscle health across the menopausal transition and aging: Finnish cohorts of middle-aged women and older women and men.European journal of clinical nutrition · 2025Article
- The acute exercise response of peripheral blood mononuclear cells and their bioenergetic function in women with high and low systemic estradiol levels.Physiological reports · 2025Article
- Body composition and functional capacity as determinants of physical activity in middle-aged and older adults: a cross-sectional analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Article
- Association between sarcopenia and cardiovascular disease according to menopausal status: findings from the China Health and Retirement Longitudinal Study (CHARLS).BMC public health · 2025Article
- A mediating role of visceral adipose tissue on the association of health behaviours and metabolic inflammation in menopause: a population-based cross-sectional study.Scientific reports · 2025Article
- Cluster of factors related to metabolic changes in older individuals: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2025Article
- Effects of voluntary wheel running on appetite-regulating peptides and neuroinflammation in the hypothalamus of ovariectomized middle-aged mice.Frontiers in molecular neuroscience · 2025Article
- The influence of menopause age on gynecologic cancer risk: a comprehensive analysis using NHANES data.Frontiers in oncology · 2025Article
- The Relationship between Physical Activity and Quality of Life in Postmenopausal Women: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Metabolic syndrome and epigenetic aging: a twin study.International journal of obesity (2005) · 2024Article
- Impact of metabolic syndrome on bone mineral density in men over 50 and postmenopausal women according to U.S. survey results.Scientific reports · 2024Article
- Body composition changes during breast cancer preventive treatment with anastrozole: Findings from the IBIS-II trial.Preventive medicine reports · 2024Article
- Article
- Variations in Postmenopausal Body Composition: A Cross-Sectional Comparison between Physical Activity Practitioners and Sedentary Individuals.Journal of functional morphology and kinesiology · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn women, metabolic health deteriorates after menopause, and the role of physical activity (PA) in mitigating the change is not completely understood. This study investigates the changes in indicators of metabolic health around menopause and evaluates whether PA modulates these changes.
methodsLongitudinal data of 298 women aged 48-55 years at baseline participating in the ERMA and EsmiRs studies was used. Mean follow-up time was 3.8 (SD 0.1) years. Studied indicators of metabolic health were total and android fat mass, waist circumference, waist-to-hip ratio (WHR), systolic (SBP) and diastolic (DBP) blood pressure, blood glucose, triglycerides, serum total cholesterol, and high- (HDL-C) and low-density (LDL-C) lipoprotein cholesterol. PA was assessed by accelerometers and questionnaires. The participants were categorized into three menopausal groups: PRE-PRE (pre- or perimenopausal at both timepoints, n = 56), PRE-POST (pre- or perimenopausal at baseline, postmenopausal at follow-up, n = 149), and POST-POST (postmenopausal at both timepoints, n = 93). Analyses were carried out using linear and Poisson mixed-effect models.
resultsAt baseline, PA associated directly with HDL-C and inversely with LDL-C and all body adiposity variables. An increase was observed in total (B = 1.72, 95% CI [0.16, 3.28]) and android fat mass (0.26, [0.06, 0.46]), SBP (9.37, [3.34, 15.39]), and in all blood-based biomarkers in the PRE-POST group during the follow-up. The increase tended to be smaller in the PRE-PRE and POST-POST groups compared to the PRE-POST group, except for SBP. The change in PA associated inversely with the change in SBP (-2.40, [-4.34, -0.46]) and directly with the change in WHR (0.72, [0.05, 1.38]).
conclusionsIn middle-aged women, menopause may accelerate the changes in multiple indicators of metabolic health. PA associates with healthier blood lipid profile and body composition in middle-aged women but does not seem to modulate the changes in most of the studied metabolic health indicators during the menopausal transition.
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