ArticleCancer imaging : the official publication of the International Cancer Imaging Society2021
Associations between dynamic-contrast enhanced MRI and tumor infiltrating lymphocytes and tumor-stroma ratio in head and neck squamous cell cancer.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Multiparametric MRI for Assessing the Tumor Microenvironment in Head and Neck Cancer: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Differential Diagnosis of Oral Salivary Gland Carcinoma and Squamous Cell Carcinoma Using Quantitative Dynamic Contrast-Enhanced MRI.Journal of clinical medicine · 2026Article
- Non-invasive PD-L1 stratification in non-small cell lung cancer using dynamic contrast-enhanced MRI.European radiology · 2025Article
- DCE-MRI quantitative analysis and MRI-based radiomics for predicting the early efficacy of microwave ablation in lung cancers.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Machine learning-based MRI radiomics for assessing the level of tumor infiltrating lymphocytes in oral tongue squamous cell carcinoma: a pilot study.BMC medical imaging · 2024Article
- Machine learning models based on quantitative dynamic contrast-enhanced MRI parameters assess the expression levels of CD3Frontiers in oncology · 2024Article
- Review
- Multiperspective quantitative tumor-stroma ratio reveals histological areas associated with poor outcomes in oral squamous cell carcinoma.Cancer medicine · 2023Article
- Use of biexponential and stretched exponential models of intravoxel incoherent motion and dynamic contrast-enhanced magnetic resonance imaging to assess the proliferation of endometrial carcinoma.Quantitative imaging in medicine and surgery · 2023Article
- Article
- Accuracy of magnetic resonance imaging in the assessment of depth of invasion in tongue carcinoma: A systematic review and meta-analysis.National journal of maxillofacial surgeryReview
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe present study used dynamic-contrast enhanced MRI (DCE-MRI) to elucidate possible associations with tumor-infiltrating lymphocytes (TIL), stroma ratio and vimentin expression in head and neck squamous cell cancer (HNSCC).
methodsOverall, 26 patients with primary HNSCC of different localizations were involved in the study. DCE-MRI was obtained on a 3 T MRI and analyzed with a whole lesion measurement using a histogram approach. TIL- and vimentin-expression was calculated on bioptic samples before any form of treatment. P16 staining was used to define HPV-status.
resultsTumor-stroma ratio correlated with entropy derived from K
conclusionsDCE-MRI might be able to reflect tumor compartments and TIL expression in HNSCC. The most promising parameters were values derived from K
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Registered trials
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