Evidence map›Paper›PMID 34801044›Full record

ArticleRespiratory research2021

Impact of COVID-19 and lockdowns on pulmonary embolism in hospitalized patients in France: a nationwide study.

Pierre Tankere, Jonathan Cottenet, Pascale Tubert-Bitter, Anne-Sophie Mariet, Guillaume Beltramo, Jacques Cadranel, Lionel Piroth, Philippe Bonniaud, Catherine Quantin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Pierre TankereReference Center for Rare Pulmonary Diseases, Pulmonary Medicine and Intensive Care Unit Department, Dijon University Hospital, BP 77908, 21079, Dijon, France.
Jonathan CottenetCHU de Dijon - Service de Biostatistique et d'Informatique Médicale, BP 77908, 21079, Dijon CEDEX, France.
Pascale Tubert-BitterUniversité Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, High-Dimensional Biostatistics for Drug Safety and Genomics, CESP, Villejuif, France.
Anne-Sophie MarietCHU de Dijon - Service de Biostatistique et d'Informatique Médicale, BP 77908, 21079, Dijon CEDEX, France.
Guillaume BeltramoReference Center for Rare Pulmonary Diseases, Pulmonary Medicine and Intensive Care Unit Department, Dijon University Hospital, BP 77908, 21079, Dijon, France.
Jacques CadranelChest Department and Constitutive Center for Rare Pulmonary Disease, Hôpital Tenon, AP-HP, Inflammation-Immunopathology-Biotherapy Department (DHU i2B) and Sorbonne Université, 75020, Paris, France.
Lionel PirothClinical Investigation Center, Clinical Epidemiology/Clinical Trials Unit, Inserm, CIC 1432, Dijon, France ; Dijon University Hospital, Dijon, France.
Philippe BonniaudReference Center for Rare Pulmonary Diseases, Pulmonary Medicine and Intensive Care Unit Department, Dijon University Hospital, BP 77908, 21079, Dijon, France.
Catherine QuantinCHU de Dijon - Service de Biostatistique et d'Informatique Médicale, BP 77908, 21079, Dijon CEDEX, France. catherine.quantin@chu-dijon.fr.ORCID http://orcid.org/0000-0001-5134-9411
Inserm · FRMaison des Sciences sociales et des Humanités de Dijon · FRUniversité Paris-Sud · FRSorbonne Université · FRUniversité de Bourgogne · FR

Funding

Agence Nationale de la Recherche ANR-20-COV1-0005-01
6 · The paper itself

Abstract

backgroundThis study assessed the impact of the COVID-19 epidemic on overall hospitalizations for pulmonary embolism (PE) in France in comparison with previous years, and by COVID-19 and non-COVID-19 status.

methodsHospitalization data (2017-2020) were extracted from the French National Discharge database (all public and private hospitals). We included all patients older than 18 years hospitalized during the 3 years and extracted PE status and COVID-19 status (from March 2020). Age, sex and risk factors for PE (such as obesity, cancer) were identified. We also extracted transfer to an intensive care unit (ICU) and hospital death. The number of PE and the frequency of death in patients in 2019 and 2020 were described by month and by COVID-19 status. Logistic regressions were performed to identify the role of COVID-19 among other risk factors for PE in hospitalized patients.

resultsThe overall number of patients hospitalized with PE increased by about 16% in 2020 compared with 2019, and mortality also increased to 10.3% (+ 1.2%). These increases were mostly linked to COVID-19 waves, which were associated with PE hospitalization in COVID-19 patients (PE frequency was 3.7%; 2.8% in non-ICU and 8.8% in ICU). The final PE odds ratio for COVID-19 hospitalized patients was 4 compared with other hospitalized patients in 2020. The analyses of PE in non-COVID-19 patients showed a 2.7% increase in 2020 compared with the previous three years.

conclusionIn 2020, the overall number of patients hospitalized with PE in France increased compared to the previous three years despite a considerable decrease in scheduled hospitalizations. Nevertheless, proactive public policy focused on the prevention of PE in all patients should be encouraged.

Indexed as

AgedAged, 80 and overCohort StudiesCommunicable Disease ControlCOVID-19FemaleFranceHospitalizationHumansMaleMiddle AgedPulmonary EmbolismRetrospective StudiesCOVID-19HospitalLockdownMedico-administrative dataPulmonary embolismSARS-COV2

Identifiers

PMID34801044
PMCPMC8605779
OpenAlexW3217273681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.