Evidence map›Paper›PMID 34800911›Full record

ArticleSchizophrenia research2022

Dissociation in patients with non-affective psychosis: Prevalence, symptom associations, and maintenance factors.

Emma Černis, Andrew Molodynski, Anke Ehlers, Daniel Freeman

Open access · hybridAbstract read
In one paragraph

Article in Schizophrenia research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Emma ČernisUniversity of Oxford Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom. Electronic address: emma.cernis@psych.ox.ac.uk.
Andrew MolodynskiOxford Health NHS Foundation Trust, Warneford Hospital, Oxford OX3 7JX, United Kingdom. Electronic address: andrew.molodynski@oxfordhealth.nhs.uk.
Anke EhlersOxford Health NHS Foundation Trust, Warneford Hospital, Oxford OX3 7JX, United Kingdom; Oxford Centre for Anxiety Disorders and Trauma, Department of Experimental Psychology, University of Oxford, The Old Rectory, Paradise Square, Oxford OX1 1TW, United Kingdom. Electronic address: anke.ehlers@psy.ox.ac.uk.
Daniel FreemanUniversity of Oxford Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford OX3 7JX, United Kingdom. Electronic address: daniel.freeman@psych.ox.ac.uk.
Oxford Health NHS Foundation Trust · GBUniversity of Oxford · GB

Funding

Department of Health NIHR-RP-2014-05-003Wellcome Trust 102176/B/13/ZWellcome Trust 200796Wellcome Trust 200796/Z/16/Z
6 · The paper itself

Abstract

Dissociation is problematic in its own right for patients with psychosis but may also contribute to the occurrence of psychotic experiences. We therefore set out to estimate in a large cohort of patients with psychosis the prevalence of dissociative experiences, and assess using network models the relationships between dissociation, its potential maintenance mechanisms, and mental health symptoms. 902 patients with non-affective psychosis attending UK mental health services participated. Both an undirected model and a partially directed network model were estimated to identify potential relationships between 'felt sense of anomaly' dissociative experiences, paranoia, hallucinations, psychological wellbeing, sleep, and six potential maintenance mechanisms (affect intolerance, perseverative thinking, general self-efficacy, alexithymia, cognitive appraisals, and cognitive-behavioural responses to dissociation). 617 patients (65.4%) had experienced at least one dissociative symptom regularly over the past fortnight, with the average number experienced being 8.9 (SD = 8.0). Dissociation had direct relationships with paranoia, hallucinations, low psychological wellbeing, cognitive appraisals, cognitive-behavioural responses to dissociation, perseverative thinking, and low alexithymia. Dissociation was a probable cause of hallucinations (94.21% of 50,000 sampled directed acyclic graphs), with a trend towards also being a cause of paranoia (86.25% of 50,000 sampled directed acyclic graphs). Approximately two-thirds of patients with psychosis experience regular dissociative experiences. Dissociation is associated with low psychological wellbeing, and it is likely to have a direct causal influence on psychotic symptoms. Catastrophic cognitive appraisals, cognitive-behavioural responses to dissociation, factors related to affect sensitivity, and perseverative thinking may contribute to the occurrence of dissociation.

Indexed as

HallucinationsPsychotic DisordersDissociative DisordersHumansParanoid DisordersPrevalenceDepersonalizationDissociationNetwork analysisPrevalencePsychological mechanismsPsychosis

Identifiers

PMID34800911
PMCPMC8765411
OpenAlexW3212078120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.