Evidence map›Paper›PMID 34800571›Full record

SynthesisJournal of affective disorders2022

Prevalence of post-traumatic stress disorder among survivors of severe COVID-19 infections: A systematic review and meta-analysis.

Ramya Nagarajan, Yuvaraj Krishnamoorthy, Vanitha Basavarachar, Raghul Dakshinamoorthy

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
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  10. Validation of the Canadian English and French Versions of the Fear of COVID-19 Scale in Quebec Nursing Staff.International journal of environmental research and public health · 2025
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  13. Co-rumination and intrapersonal cognitive processes predict distress: Longitudinal evidence from the COVID-19 pandemic.Stress and health : journal of the International Society for the Investigation of Stress · 2024
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  18. Fear of COVID-19 and PTSD: The Protective Function of Problem-Solving Appraisals in Mental Health.International journal of environmental research and public health · 2024
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  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Ramya NagarajanNational Institute of Epidemiology, Chennai, India. Electronic address: nagarajanramya55@gmail.com.
Yuvaraj KrishnamoorthyDepartment of Community Medicine, ESIC medical College and PGIMSR, Chennai, India.
Vanitha BasavaracharDepartment of Community Medicine, Bowring and Lady Curzon Medical College and Research Institute, Bengaluru, India.
Raghul DakshinamoorthyDepartment of Orthopedics, Institute of medical Sciences, Banaras Hindu University, Varanasi, India.
Banaras Hindu University · INBangalore Medical College and Research Institute · INESIC Hospital · INNational Institute of Epidemiology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-traumatic stress disorder (PTSD) develops after a person has experienced a traumatic event which can be highly accounted for amidst the ongoing COVID-19 pandemic. This study aims to estimate the prevalence of PTSD among the severe cases of COVID-19.

methodsWe included the observational studies done to estimate the burden of PTSD among severe COVID-19 patients. Data was extracted manually using structured data extraction form and analyzed in STATA version 14.2. A random-effects model was applied, and the final pooled data was reported as proportion with a 95% confidence interval. Multivariable meta-regression analysis was carried out, and a forest plot was utilized to represent the study-specific and pooled estimates for overall and subgroup analysis.

resultsWe included 13 articles with 1,093 participants in our analysis. The pooled prevalence was estimated to be 16% (95%CI: 9% to 23%). We found a substantial heterogeneity between the studies that reported the outcome (I LIMITATIONS: We found significant between-study variability for the outcome. In addition, our review was found to have substantial publication bias. We also found that the lower quality of the majority of the studies being included in our review.

interpretationOur study states that the risk of PTSD is higher following severe COVID-19 infection. Understanding this burden will help us in diverting the resources and adapting necessary interventions to control the situation.

Indexed as

COVID-19Stress Disorders, Post-TraumaticHumansPandemicsPrevalenceSARS-CoV-2SurvivorsCOVID-19HospitalizationICU admissionPTSD

Identifiers

PMID34800571
PMCPMC8596764
OpenAlexW3211345487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.