ReviewAdvanced drug delivery reviews2022
Antimicrobial blue light: A 'Magic Bullet' for the 21st century and beyond?
Review in Advanced drug delivery reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05739058 (Violet-Blue Light Inactivation of Bacteria in Chronic Wounds), which is not on this map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Violet-Blue Light Inactivation of Bacteria in Chronic Wounds
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- The Use of Blue Light as an Antimicrobial Treatment Against Staphylococcus aureus: A Systematic Review.Lasers in surgery and medicine · 2026Pooled it
- Antimicrobial Efficacy of Endogenous Blue Light Photoinactivation (400-470 nm) AgainstMedical sciences (Basel, Switzerland) · 2026Pooled it
- Antimicrobial blue light inactivatesFood chemistry: X · 2026Article
- Smartphone-Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Blue Light-Mediated Nitric Oxide-Releasing Formulation for the Multimodal Treatment of Acne Vulgaris.Advanced healthcare materials · 2026Article
- Experiences and theory reveal a decrease in antimicrobial blue light killing efficiency as biofilm grows in a Pseudomonas aeruginosa model.Scientific reports · 2026Article
- Multispectral Antimicrobial Blue Light (aBL) Systems for Continuous Decontamination of Food-Contact Surfaces and Environmental Matrices.Foods (Basel, Switzerland) · 2026Article
- Article
- Biochemical indicators of inflammatory response in leukemia patients with picc-associated phlebitis: Evaluation of basic fibroblast growth factor combined with light therapy.Journal of medical biochemistry · 2026Article
- Evaluation of the Inactivation of Microorganisms by a Blue Laser (445 nm)-An In Vitro Study.Antibiotics (Basel, Switzerland) · 2026Article
- Lighting the way or casting new shadows? A One Health perspective on light-based technologies against clinically important antimicrobial-resistant bacteria.Frontiers in cellular and infection microbiology · 2026Article
- Interference of phototherapy with blue LED light on the behaviour of mice infected with Toxoplasma gondii.PloS one · 2026Article
- Biomolecules involved in the metabolism of Escherichia coli affected by photodynamics: A calorimetry study.PloS one · 2026Article
- Antibiotic: a boon to mankind and doom to the environment - an insight on biological and non-biological degradation processes.Frontiers in microbiology · 2026Review
- The "Irradiance Effect" Plays a Crucial Role in the Photosensitization ofMolecules (Basel, Switzerland) · 2025Article
- Beyond Resistance: Tolerance and Resilience of Bacteria to Photodynamic and Oxidative Stress.International journal of molecular sciences · 2025Review
- Lights out for Superbugs: Is antimicrobial blue light a potential approach for future infection Control?Advanced drug delivery reviews · 2025Review
- Assessing 5-Aminolevulinic Acid as a Natural Biocide Precursor for Light-Activated Eradication ofInternational journal of molecular sciences · 2025Article
- Article
- Protocol for a randomized clinical trial on the efficacy of blue light emitting diode in the treatment of recurrent vulvovaginal candidiasis.Lasers in medical science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
Over the past decade, antimicrobial blue light (aBL) at 400 - 470 nm wavelength has demonstrated immense promise as an alternative approach for the treatment of multidrug-resistant infections. Since our last review was published in 2017, there have been numerous studies that have investigated aBL in terms of its, efficacy, safety, mechanism, and propensity for resistance development. In addition, researchers have looked at combinatorial approaches that exploit aBL and other traditional and non-traditional therapeutics. To that end, this review aims to update the findings from numerous studies that capitalize on the antimicrobial effects of aBL, with a focus on: efficacy of aBL against different microbes, identifying endogenous chromophores and targets of aBL, Resistance development to aBL, Safety of aBL against host cells, and Synergism of aBL with other agents. We will also discuss our perspective on the future of aBL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.