Evidence map›Paper›PMID 34800445›Full record

SynthesisThe Science of the total environment2022

A systematic review of outdoor airborne fungal spore seasonality across Europe and the implications for health.

Samuel Anees-Hill, Philippa Douglas, Catherine H Pashley, Anna Hansell, Emma L Marczylo

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Pooled it
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  11. Validity of anJournal of asthma and allergy · 2026
    Article
  12. Birch rust allergy as a novel autumnal trigger of seasonal airway symptoms.The journal of allergy and clinical immunology. Global · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel Anees-HillCentre for Environmental Health and Sustainability, University of Leicester, Leicester LE1 7LW, UK; The National Institute of Health Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester LE1 7LW, UK. Electronic address: sph22@leicester.ac.uk.
Philippa DouglasThe National Institute of Health Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester LE1 7LW, UK; Environmental Hazards and Emergencies Department, UK Health Security Agency, Harwell Campus, Chilton, Oxfordshire OX11 0RQ, UK. Electronic address: philippa.douglas@phe.gov.uk.
Catherine H PashleyThe National Institute of Health Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester LE1 7LW, UK; Department of Respiratory Sciences, Institute for Lung Health, University of Leicester, Leicester LE1 7RH, UK. Electronic address: chp5@leicester.ac.uk.
Anna HansellCentre for Environmental Health and Sustainability, University of Leicester, Leicester LE1 7LW, UK; The National Institute of Health Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester LE1 7LW, UK. Electronic address: ah618@leicester.ac.uk.
Emma L MarczyloThe National Institute of Health Research Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester LE1 7LW, UK; Toxicology Department, UK Health Security Agency, Harwell Campus, Chilton, Oxfordshire OX11 0RQ, UK. Electronic address: emma.marczylo@phe.gov.uk.
University of Leicester · GBPublic Health England · GB

Funding

Medical Research Council MR/P023673/2
6 · The paper itself

Abstract

Fungal spores make up a significant proportion of organic matter within the air. Allergic sensitisation to fungi is associated with conditions including allergic fungal airway disease. This systematic review analyses outdoor fungal spore seasonality across Europe and considers the implications for health. Seventy-four studies met the inclusion criteria, the majority of which (n = 64) were observational sampling studies published between 1978 and 2020. The most commonly reported genera were the known allergens Alternaria and Cladosporium, measured in 52 and 49 studies, respectively. Both displayed statistically significant increased season length in south-westerly (Mediterranean) versus north-easterly (Atlantic and Continental) regions. Although there was a trend for reduced peak or annual Alternaria and Cladosporium spore concentrations in more northernly locations, this was not statistically significant. Peak spore concentrations of Alternaria and Cladosporium exceeded clinical thresholds in nearly all locations, with median peak concentrations of 665 and 18,827 per m

Indexed as

Air MicrobiologyEnvironmental MonitoringAlternariaEuropeSeasonsSpores, FungalAerobiologyAlternariaCladosporiumFungiOutdoor airSeason

Identifiers

PMID34800445
PMCPMC8919338
OpenAlexW3214285562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.