ArticleClinical journal of oncology nursing2021
Clinical Trial Participation: A Pilot Study of Patient-Identified Barriers.
Article in Clinical journal of oncology nursing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05398471 (Observational Clinical Trial Appraising Medical Trial Experiences of Rheumatoid Arthritis Patients Participating In Clinical Research), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Observational Clinical Trial Appraising Medical Trial Experiences of Rheumatoid Arthritis Patients Participating In Clinical Research
Who cites it
17 citing papers in PubMed.
- Participants' Perspectives on Health Impact, Barriers and Facilitators to Adherence in a Mediterranean Diet Lifestyle Trial.Nutrients · 2025Trial
- Planned time burden for patients participating in phase 2 cancer trials.The oncologist · 2026Article
- Scoping review of oncology clinical trials nursing: Roles, competencies, and evolving practice in cancer research.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2026Article
- Perceptions of health research participation in rural and urban Pennsylvanians.Journal of clinical and translational science · 2026Article
- Article
- Advancing Equity and Patient Partnership in Clinical Trials for Inflammatory Bowel Disease: A Model for Inclusive Trial Design.Clinical and experimental gastroenterology · 2026Article
- Early detection of osteoporosis in adult children of patients with proximal femur fractures: a real-world screening study.BMC musculoskeletal disorders · 2025Article
- Characteristics of clinical trials associated with appeal and return on investment to participants: a review and framework.The oncologist · 2025Review
- Detecting Conversation Topics in Recruitment Calls of African American Participants to the All of Us Research Program Using Machine Learning: Model Development and Validation Study.JMIR formative research · 2025Article
- The participants' perspective on facioscapulohumeral muscular dystrophy trials in The Netherlands - A qualitative study.Journal of neuromuscular diseases · 2025Article
- Clinical trial knowledge, discussion, and participation among cancer survivors: A HINTS-SEER study.Patient education and counseling · 2025Article
- Primary care patient interests in joining a planned multi-cancer early detection clinical trial.Cancer medicine · 2024Article
- Patient engagement and satisfaction with early phase cell therapy clinical trials at a tertiary inflammatory bowel disease center.Stem cell reports · 2024Article
- Development and validation of a drug clinical trial participation feelings questionnaire for cancer patients.Frontiers in pharmacology · 2024Article
- Development of a Japanese Scale that Evaluates the Level of Nursing Support Provided to Patients for Decision-Making in Cancer Clinical Trials.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023Article
- Benefits of Participation in Clinical Trials: An Umbrella Review.International journal of environmental research and public health · 2022Review
- Characteristics, attitudes, and the odds for positive attitude toward clinical trial: A study on Indonesian COVID-19 vaccine trial participants.Perspectives in clinical researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundClinical trial enrollment in the United States is lacking, particularly among older adult and ethnic and racial minority populations.
objectivesThe aim of the current study was to identify patient-related barriers to clinical trial participation using a mixed-methods patient survey and to offer insights to develop evidence-based implementation strategies to address these barriers.
methodsA retrospective survey was conducted of patients who were not interested in participating in a clinical trial to quantify the reasons these patients chose not to participate. Directed qualitative content analysis was used to identify themes that emerged from the write-in responses.
findingsThe greatest patient-reported barriers were misperceptions about placebos, a desire to not feel like a human guinea pig, uncertainty surrounding clinical trial treatment effectiveness compared to standard care, and concerns about additional appointments or tests. Oncology nurses can address patient enrollment barriers by providing targeted education and participating in the informed consent process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.