Evidence map›Paper›PMID 34799973›Full record

ArticleAging cell2021

Mitochondrial aconitase 1 regulates age-related memory impairment via autophagy/mitophagy-mediated neural plasticity in middle-aged flies.

Yun-Ho Cho, Gye-Hyeong Kim, Joong-Jean Park

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Active zone plasticity couples sleep need to presynaptic hypophosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  14. Protein modification regulated autophagy inFrontiers in physiology · 2023
    Review
  15. Insights fromFrontiers in neuroscience · 2023
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yun-Ho ChoDepartment of Physiology, Korea University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-6790-0308
Gye-Hyeong KimDepartment of Physiology, Korea University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-2912-1215
Joong-Jean ParkDepartment of Physiology, Korea University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-4534-3002
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related memory impairment (AMI) occurs in many species, including humans. The underlying mechanisms are not fully understood. In wild-type Drosophila (w

Indexed as

Aconitate HydrataseAnimalsAutophagyHumansMemory DisordersMiddle AgedMitochondriaMitophagyNeuronal PlasticityAconitate Hydrataseaconitaseage-related memory disordersautophagymitochondriamitophagyneural plasticity

Identifiers

PMID34799973
PMCPMC8672789
OpenAlexW3212665399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.